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Mutation research pp 452–468Cite as

Applied mutation research

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Abstract

The application of mutation research to concerns of the human society poses its own problems and requires its own techniques. It is a wide field. In this chapter, I can do no more than indicate the nature of the problems, very briefly mention some of the techniques, and provide references for further reading.

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References

  1. Nilan, R.A. (1973), ‘Increasing the effectiveness, efficiency and specificity of mutation induction in flowering plants’, In: ‘Genes, Enzymes and Populations’, pp. 205–222, ed. A. Srb, Plenum Publ. Corporat.

    Google Scholar 

  2. Khvostova, V.V. and Tarasenko, N.D. (1970), ‘Problems of the specificity of experimental mutagenesis in higher plants’, Uspekhi sovremmennio biologii 69, 409–423.

    CAS  Google Scholar 

  3. Jain, H.K., Raut, R.N. and Khamankar, Y.G. (1968), Base specific chemicals and mutation analysis in Lycopersicon, Heredity 23, 247–256.

    Article  PubMed  CAS  Google Scholar 

  4. Swaminathan, M.S. (1969), ‘Mutation Breeding’, Proc. 12th Int. Congr. Genetics, 3, 327–347 (Science Council of Japan).

    Google Scholar 

  5. Melchers, G. (1972), ‘Haploid higher plants for plant breeding’, Z Pflanzenzüchtg. 67, 19–32.

    Google Scholar 

  6. Nickeil, L.G. and Heinz, D.J. (1973), ‘Potential of cell and tissue culture techniques as aids in economic plant improvement’, In: ‘Genes, enzymes and population’, pp. 109–128, ed. A. Srb, Plenum Publ. Corporat.

    Google Scholar 

  7. Gaul, H. (1965), ‘Induced mutations in plant breeding’, In ‘Genetics Today’ vol. 3, Pergamon Press, New York, 689–709.

    Google Scholar 

  8. Smith, R.H. and Borstel, von R.C. (1972), ‘Genetic control of insect populations’, Science 178, 1164–1174.

    Article  PubMed  CAS  Google Scholar 

  9. Serebrovsky, A.S. (1940), ‘On the possibility of a new method for the control of insect pests’, Zool. Zh. 19, 618–630.

    Google Scholar 

  10. Curtis, C.F. (1968), ‘A possible genetic method for the control of insect pests, with special reference to tsetse flies (Glossina spp)’, Bull Ent. Res. 57, 509–523.

    Article  CAS  Google Scholar 

  11. Denell, R.E. (1973), ‘Use of male sterilization mutations for insect control programmes’, Nature 242, 274–275.

    Article  PubMed  CAS  Google Scholar 

  12. Alper, T. (1967), ‘Application of radiobiology in radiotherapeutic developments’, In: ’Modern Trends in Radiotherapy I., pp. 1–33, ed., Deeley and Wood, Butterworth.

    Google Scholar 

  13. ‘The hazards to man of nuclear and allied radiations’, Medical Research Council, London, Her Majesty’s Stationery Office, 1956.

    Google Scholar 

  14. ‘The biological effects of atomic radiation’. Summary reports from a study by the National Acad. Sciences. Nat. Res. Council, Washington, D.C. 1956.

    Google Scholar 

  15. ‘The effects on populations of exposure to low levels of ionizing radiation’. Report of the advisory committee on the biological effects of ionizing radiation. Division of medical sciences. Nat. Acad. Sci. USA, Nat. Res. Council, Washington, D.C. 1972.

    Google Scholar 

  16. ‘Ionizing radiation: levels and effects’. A report of the United Nations Scientific Committee on the effects of atomic radiation. 2 volumes. United Nations New York. 1972.

    Google Scholar 

  17. ‘Report of the United Nations Scientific Committee on the Effects of Atomic Radiation’. General Assembly, official records: 27th session. Suppl. No. 25 (A/8725) 1972.

    Google Scholar 

  18. Sankaranarayanan, K. (1974), ‘Recent advances in the assessment of genetic hazards of ionizing radiation’, Atomic Energy Review 12, 47–74.

    PubMed  CAS  Google Scholar 

  19. Searle, A.G. (1974), ‘Mutation induction in mice’ Adv. Rad. Biol. 4, 131–207.

    Google Scholar 

  20. Crow, F.J. (1957), ‘Possible consequences of an increased mutation rate’, Eugenics Quarterly 4, 67–80.

    Google Scholar 

  21. Uchida, I.A., Holunga, R. and Lawler, C. (1968), ‘Maternal radiation and chromosomal aberration’. Lancet II, 1045–1049.

    Article  Google Scholar 

  22. Yamomoto, M., Shimada, T., Endo, A. and Watanabe, G. (1973), ‘Effects of low-dose X-radiation on the chromosomal non-disjunction in aged mice’. Nature New Biology 244, 206–207.

    Article  Google Scholar 

  23. Bridges, B.A. (1974), ‘The three-tier approach to mutagenicity screening and the concept of radiation-equivalent dose’. Mutation Res. 26, 335–340.

    Article  PubMed  CAS  Google Scholar 

  24. Vig, B.K. (1973), ‘Somatic crossing over in Glycine max (L) Merrill: effect of some inhibitors of DNA synthesis on the induction of somatic crossing over and point mutations’, Genetics 73, 583–596.

    PubMed  CAS  Google Scholar 

  25. Fries, N. and Kihlman, B. (1948), ‘Fungal mutations obtained with methylxanthines’, Nature 162, 573.

    Article  PubMed  CAS  Google Scholar 

  26. Novick, A. and Szilard, L. (1951), ‘Experiments on spontaneous and chemically induced mutations growing in the chemostat’, Cold Spring Harbor Symp. Quant. Biol. 16, 337–343.

    Article  PubMed  CAS  Google Scholar 

  27. Cattanach, B.M. (1962), ‘Genetical effects of caffeine in mice’, Zeitschr. Vererb. Lehre. 93, 215–219.

    CAS  Google Scholar 

  28. Lyon, M.F., Phillips, J.S.R. and Searle, A.G. (1962), ‘A test for mutagenicity of caffeine in mice’, Zeitschr. Vererb. Lehre. 93, 7–13.

    CAS  Google Scholar 

  29. Kihlman, B.A. and Levan, A. (1949), ‘The cytological effect of caffeine’, Hereditas 35, 109–111.

    CAS  Google Scholar 

  30. Ostertag, W., Duisberg, E. and Stürmann, M. (1965), ‘The mutagenic activity of caffeine in man’, Mutation Res. 2, 293–296.

    Article  PubMed  CAS  Google Scholar 

  31. Loprieno, N. and Schüpbach, M. (1971), ‘On the effect of caffeine on mutation and recombination in Schizosaccharomyces pombe’, Molec. Gen. Genetics 110, 348–354.

    Article  CAS  Google Scholar 

  32. Boveri, T. (1929), ‘The origin of malignant tumors’, Williams and Wilkins, Baltimore.

    Google Scholar 

  33. Ames, B.N., Durston, W.E., Yamasaki, E. and Lee, F.D. (1974), ‘Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection’, Proc. Nat. Acad. Sci. U.S.A. 70, 2281–2285.

    Article  Google Scholar 

  34. Maher, V.M., Douville, D., Tomura, T. and Lancker, van J.L. (1974), ‘Mutagenicity of reactive derivatives of carcinogenic hydrocarbons: evidence of DNA repair’, Mutation Res. 23, 113–128.

    Article  PubMed  CAS  Google Scholar 

  35. Isono, K. and Yourno, J. (1974), ‘Chemical carcinogens as frameshift mutagens: Salmonella DNA sequence sensitive to mutagenesis by poly cyclic carcinogens’, Proc. Nat. Acad. Sci. U.S.A. 71, 1612–1617.

    Article  CAS  Google Scholar 

  36. Commoner, B., Vithayathil, A.J. and Henry, J.I. (1974), ‘Detection of metabolic carcinogen intermediates in urine of carcinogen-fed rats by means of bacterial mutagenesis’, Nature 249, 850–852.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Animal Genetics, University of Edinburgh, UK

    Charlotte Auerbach F.R.S. (Professor Emeritus)

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  1. Charlotte Auerbach F.R.S.
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© 1976 Charlotte Auerbach

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Auerbach, C. (1976). Applied mutation research. In: Mutation research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3103-0_23

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  • DOI: https://doi.org/10.1007/978-1-4899-3103-0_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-11280-5

  • Online ISBN: 978-1-4899-3103-0

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