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Mammalian Metabolism of Flavonoids

  • Chapter
The Flavonoids

Abstract

Although earlier investigations of the mammalian metabolism of flavonoid compounds were largely concerned with the identification of their urinary metabolites (cf. De Eds, 1968), more recent studies have centred on the role of the intestinal microflora in the catabolism of flavonoid molecules, on the significance of the biliary-enteric route of excretion and on the disposition of flavonoids in mammalian tissues following oral and parenteral administration. Additionally the introduction of chemically modified flavonoids and of synthetic phenylchro-mones as therapeutic agents has promoted metabolic and pharmacokinetic investigations on compounds showing close structural relationships with the naturally occurring flavonoids.

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  1. Leslie A. Griffiths
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Editors and Affiliations

  1. Department of Botany, University of Reading, UK

    J. B. Harborne (Professor) (Professor)

  2. Department of Botany, University of Texas at Austin, USA

    T. J. Mabry (Professor) (Professor)

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Griffiths, L.A. (1982). Mammalian Metabolism of Flavonoids. In: Harborne, J.B., Mabry, T.J. (eds) The Flavonoids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2915-0_12

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