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Mixed cryoglobulinemia: the role of HCV and organ-specific antibodies

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Abstract

The term ‘cryoglobulin’ was introduced to define a group of proteins which have the common property of forming a reversible precipitate or gel in the cold [1]. Three groups of cryoglobulins have been identified. Type I cryoglobulins are monoclonal, the most common one being immunoglobulin M (IgM), a protein associated with immunoprolifera-tive disorders, such as Waldenstrom’s macroglobulinemia, lymphopro-liferative disorders and multiple myeloma.

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Bombardieri, S. et al. (1996). Mixed cryoglobulinemia: the role of HCV and organ-specific antibodies. In: Ansell, B.M., Bacon, P.A., Lie, J.T., Yazici, H. (eds) The Vasculitides. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2889-4_20

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  • DOI: https://doi.org/10.1007/978-1-4899-2889-4_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-64140-4

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