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Drug interactions

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Therapeutics in Rheumatology

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Abstract

The physician of the 1980s has a vast therapeutic armamentarium at his disposal with which to treat his patient. While in some countries, e. g. Germany, the number of preparations may exceed 10 000, in the UK some 3000 preparations are listed in the monthly index of medical supplies (MIMS). There are perhaps 1000 pharmacologically active drugs available for prescription and the potential pairs of drugs that might interact is therefore about 500 000. Patients admitted to hospital on average receive 4 or 5 drugs during the course of a hospital admission, and one in every five patients receives at least ten drugs (Crooks and Moir, 1974). There is little doubt that in the last ten years the exposure of patients to drugs has increased and this applies to both hospital and general practice.

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Authors
  1. M. C. L’E. Orme
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Editors and Affiliations

  1. Sheffield Centre for Rheumatic Diseases, Nether Edge Hospital, Sheffield, UK

    J. M. H. Moll BSc DM PhD FRCP (Consultant physician in Rheumatology and Head, Honorary Clinical Lecturer in Rheumatic Diseases) (Consultant physician in Rheumatology and Head, Honorary Clinical Lecturer in Rheumatic Diseases)

  2. University of Sheffield, UK

    J. M. H. Moll BSc DM PhD FRCP (Consultant physician in Rheumatology and Head, Honorary Clinical Lecturer in Rheumatic Diseases) (Consultant physician in Rheumatology and Head, Honorary Clinical Lecturer in Rheumatic Diseases)

  3. General Infirmary at Leeds, University Department of Medicine, UK

    H. A. Bird MA MD FRCP (Lecturer in Rheumatology, Honorary Consultant Rheumatologist) (Lecturer in Rheumatology, Honorary Consultant Rheumatologist)

  4. General Infirmary at Leeds and Royal Bath Hospital, Harrogate, UK

    H. A. Bird MA MD FRCP (Lecturer in Rheumatology, Honorary Consultant Rheumatologist) (Lecturer in Rheumatology, Honorary Consultant Rheumatologist)

  5. Clinical Research Department, Imperial Chemical Industries PLC, Pharmaceuticals Division, Alderley Park, Macclesfield, UK

    A. Rushton MB ChB MRCP (Drug team leader) (Drug team leader)

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© 1986 J. M. H. Moll, H. A. Bird and A. Rushton

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Orme, M.C.L. (1986). Drug interactions. In: Moll, J.M.H., Bird, H.A., Rushton, A. (eds) Therapeutics in Rheumatology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2883-2_3

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