Abstract
The three main crystal-deposition disorders encountered in clinical practice are those associated with urate, pyrophosphate, and hydroxyapatite. The three types of crystal deposited in relation to tissues of the locomotor system are characterized by somewhat different clinical presentations and therapeutic needs. Although this chapter will be largely devoted to the ‘classical’ crystal deposition disease, urate gout, brief comments will also be made on the management of other crystal-deposition states the rheumatologist is likely to encounter in clinical practice.
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References
Auerbach, R. and Orentrich, N. (1968) Alopecia and ichthyosis secondary to allopurinol. Arch. Dermatol., 98, 104.
Bayliss, R., Clarke, C., Whitehead, T. P. and Whitfield, A. G. W. (1984) The management of hyperuricaemia. J. R. Coll. Phys. Lond., 18, 144–6.
Begemann, H. and Neu, I. (1975) Die behandlung der urikopathie mit benz bromaronum unter besonderer berucksichtigune der neireninsuffizienz. Therapie, 25, 2184–94.
Boardman, P. L. and Hart, F. D. (1967) Side effects of indomethacin. Ann. Rheum. Dis., 26, 127–32.
Boger, W. P. and Strickland, S. C. (1955) Probenecid (Benemid) . Arch. Intern. Med., 95, 83–92.
Brenner, W. J. and Paulsen, C. A. (1976) Colchicine and testicular function in man. N. Engl. J. Med., 294, 1384–5.
Brewis, I., Ellis, R. M. and Scott, J. T. (1975) Single daily dose of allopurinol. Ann. Rheum. Dis., 34, 256–9.
Brogard, J. M., Frankhauser, J. and Stahl, A. (1973) Application de l’uricolyse enzymatique au traitement des hyperuricemies d’origine renal. Schweizer. Med. Wochens., 103, 404–10.
Buchanan, W. W., Klinenberg, J. R. and Seegmiller, J. E. (1965) The inflammatory response to injected microcrystalline monosodium urate in normal, hyperuricaemic, gouty and uremic subjects. Arth. Rheum., 8, 361.
Burns, J. J., Yü, T-F. and Berger, L. (1958) Zoxazolamine: physiological disposition, uricosuric properties. Am. J. Med., 25, 401–8.
Cannon, P. J., Heinemann, H. O., Stason, W. B. and Laragh, J. H. (1965) Ethacrynic acid. Effectiveness and mode of diuretic action in man. Circulation, 31, 5–18.
Cartier, P. H. and Hamet, M. (1973) Mechanism of antiuric action of 4-oxy and 4thiopyrazolopyrimidines. Biochem. Pharmacol., 22, 3061–75.
Caruso, I., Fumagalli, M., Marcolongo, R. and Sacchetti, G. (1977) Indoprofen for acute gouty arthritis (letter). Arthr. Rheum., 20, 1438–9.
Coombs, F. S., Pecora, L. J., Thorogood, E. et al. (1940) Renal function in patients with gout. J. Clin. Invest., 19, 525–35.
Cuq, P. (1973) Experience française du traitement de la crise de goutte aigue par le naproxen-C1674. Scand. J. Rheumatol., (Suppl.) 2, 64–8.
Delbarre, F., Auscher, C., Gery, A., Brouilheb, H. and Olivier, J. L. (1968) Le traitement de la dyspurinie goutteuse par la mercaptopyrazolopyrimidine (MPP: thiopurinol). Presse Med., 76, 2329–32.
Demartini, F. E. (1965) Hyperuricaemia induced by drugs. Arthr. Rheum., 8, 823–9.
De Seze, S., Ryckewaert, A., Caroit, M. et al. (1964) Congres International de la Goutte et de la Lithiase Urique. Sept. 4, Evian, p. 297.
Dixon, A. St. J. (1963) Salicylates and uric acid excretion, in Salicylates. An International Symposium (eds A. St. J. Dixon, B. K. Martin, M. J. H. Smith and P. H. N. Ward), Churchill Livingstone, London, p. 38.
Dreyfuss, F. (1960) The role of hyperuricaemia in coronary heart disease. Dis. Chest, 38, 332–4.
Eidlitz, M. (1961) Uric acid and arteriosclerosis. Lancet, ii, 1046–7.
Elion, G. B., Kovensky, A. and Hitchings, G. H. et al. (1966) Metabolic studies of allopurinol, an inhibitor of xanthine oxidase. Biochem. Pharmacol., 15, 863–80.
Emmerson, B. T. (1963) A comparison of uricosuric agents in gout, with special reference to sulphinpyrazone. Med. J. Austr., 50, 839–44.
Ferris, T. F., Morgan, W. S. and Levitin, H. (1961) Nephrotic syndrome caused by probenecid. N. Engl. J. Med., 265, 381–3.
Fessel, W. J. (1972) Hyperuricaemia in health and disease. Seminars Arthr. Rheum., 1, 275.
Fessel, W. J. (1979) Renal outcomes of gout and hyperuricaemia. Am. J. Med., 67, 74–82.
Fox, I. H. (1977) Hypouricaemic agents in the treatment of gout, in Clinics in Rheumatic Diseases, Vol. 3, No. 1. Crystal Induced Arthropathies (ed W. N. Kelley), Saunders, London, p. 148.
Glick, E. N. (1961) Sulphinpyrazone in the treatment of arthritis associated with hyperuricaemia. Proc. R. Soc. Med., 54, 423–6.
Graham, R. and Scott, J. T. (1970) Clinical survey of 354 patients with gout. Ann. Rheum. Dis., 29, 461–8.
Greenberg, M. S. and Zambarano, S. S. (1972) Aplastic agranulocytosis after allopurinol therapy. Arthr. Rheum., 15, 413–6.
Gutman, A. B. and Yü, T-F. (1951) Benemid (p-(di-n-propylsulfamyl)-benzoid acid) as uricosuric agent in chronic gouty arthritis. Trans. Assoc. Am. Phys., 64, 279–88.
Gutman, A. B. and Yü, T-F. (1952) Gout, a derangement of purine metabolism. Adv. Inter. Med., 5, 227.
Gutman, A. B. and Yü, T-F. (1955) Prevention and treatment of chronic gout. J. Am. Med. Assoc., 157, 1096–102.
Hall, A. P. (1965) Correlations among hyperuricaemia, hypercholesterolism, coronary disease and hypertension. Arthr. Rheum., 8, 846–52.
Hall, A. P., Barry, P. E., Dawber, T. R. and McNamara, P. M. (1967) Epidemiology of gout and hyperuricaemia. A long-term population study. Am. J. Med., 42, 27–37.
Hansen, O. E. (1966) Hyperuricaemia, gout and atherosclerosis. Am. Heart J., 72, 570–3.
Hensen, O. E. and Holten, C. (1958) Uricosuric effect of dicoumarol. Lancet, i, 1047–8.
Hart, F. D. and Boardman, P. L. (1963) Indomethacin: a new non-steroid antiinflammatory agent. Br. Med. J., 2, 965–70.
Hertz, P., Yager, H. and Richardson, J. A. (1972) Probenecid-induced nephrotic syndrome. Arch. Pathol., 94, 241.
Holmes, E. W. (1977) Pathogenesis of hyperuricaemia in primary gout, in Clinics in Rheumatic Diseases, Vol. 3, No. 1. Crystal-Induced Arthropathies (ed. W. N. Kelley), Saunders, London, p. 15.
Hutchinson, J. C. and Wilkinson, W. H. (1973) The uricosuric action of halofenate (MK-185) in patients with hyperuricaemia or uncomplicated primary gout and hyperlipidemia. Atherosclerosis, 18, 353–62.
Irby, R., Toone, E. and Owen, D. (1966) Bone marrow depression associated with allopurinol therapy. Arthr. Rheum., 9, 860.
Jain, A. K., Ryan, J. R. and McMahon, F. G. (1976) Comparison of ticrynafen and probenecid in treatment of hyperuricemia. Clin. Res., 24, 43A.
Jakovcic, S. and Sorensen, C. B. (1967) Studies of uric acid metabolism in glycogen storage disease associated with gouty arthritis. Arthr. Rheum., 10, 129–34.
Jarzobski, J., Ferry, J., Wombolt, D., Fitch, D. M. and Egan, J. D. (1970) Vasculitis with allopurinol therapy. Am. Heart J., 79, 116–21.
Johnson, H. P., Engleman, E. P., Forsham, P. H. et al. (1954) Effects of phenylbutazone in gout. N. Engl. J. Med., 250, 665.
Kaegi, A., Pineo, G. F., Shimizu, A., Trivedi, H., Hirsh, J. and Gent, M. (1974) Arteriovenous-shunt thrombosis: prevention by sulfinpyrazone. N. Engl. J. Med., 290, 304–6.
Kantor, G. L. (1970) Toxic epidermal necrolysis, azotemia, and death after allopurinol therapy. J. Am. Med. Assoc., 212, 478–9.
Kaplan, H. (1960) Sarcoid arthritis with a response to colchicine. N. Engl. J. Med., 263, 778–81.
Kelley, W. N. (1975a) Effects of drugs on uric acid in man. Ann. Rev. Pharmacol., 15, 327–50.
Kelley, W. N. (1975b) Pharmacologic approach to the maintenance of urate homeostasis. Nephron, 14, 99–115.
Kelley, W. N. (1979) Treatment of hyperuricemia, in Arthritis and Allied Conditions. A Textbook of Rheumatology (ed D. J. McCarty), 9th edn, Lea and Febiger, Philadelphia, p. 1231.
Kelley, W. N., Greene, M. L., Rosenbloom, F. M., Henderson, J. F. and Seegmiller, J. E. (1969) Hypoxanthine-gnomic phosphoribosyltransferase deficiency in gout. Ann. Intern. Med., 70, 155–206.
Kelley, W. N., Rosenbloom, E. M., Henderson, J. F. et al. (1967) A specific enzyme defect in gout associated with overproduction of uric acid. Proc. Nat. Acad. Sci. USA, 57, 1735.
Kelley, W. N. and Wyngaarden, J. B. (1971) Drug treatment of gout. Seminars Drug Treat., 1, 119–47.
Kidd, E. G., Boyce, K. C. and Freyberg, R. H. (1953) Clinical studies of phenylbutazone (Butazolidin) and butapyrine (Irgapyrine) in rheumatoid arthritis, rheumatoid spondylitis and gout. Ann. Rheum. Dis., 12, 20–4.
Kissel, P., Mauuary, G., Royer, R. and Toussain, P. (1975) Treatment of malignant haemopathies and urate oxidase. Lancet, 1, 229.
Klinenberg, J. R. (1977) The management of asymptomatic hyperuricaemia, in Clinics in Rheumatic Diseases, Vol. 3, No. 1. Crystal-Induced Arthropathies (ed W. N. Kelley), Saunders, London, p. 159.
Kuzell, W. C., Glover, R. P., Gibbs, J. O. et al. (1964) Effect of sulfinpyrazone on serum uric acid in gout. A long-term study. Genetics, 19, 894–909.
Kuzell, W. C., Schaffarzick, R. W., Brown, B. and Mankle, E. A. (1952) Phenylbutazone (Butazolidin) in rheumatoid arthritis and gout. J. Am. Med. Assoc., 149, 729–34.
Lesch, M. and Nyhan, W. L. (1964) A familial disorder of uric acid metabolism and central nervous system function. Am. J. Med., 36, 561–70.
Lidsky, M. D. and Sharp, J. T. (1967) Jaundice with the use of 4-hydroxypyrazolo (3, 4-D) pyrimidine (4-HPP) (Abstract). Arthr. Rheum., 10, 294.
Loebl, W. Y. and Scott, J. T. (1974) Withdrawal of allopurinol in patients with gout. Ann. Rheum. Dis., 33, 304–7.
MacLachlan, M. J. and Rodnan, G. P. (1967) Effects of food and alcohol in serum uric acid and acute attacks of gout. Am. J. Med., 42, 38–57.
McCarty, D. J. (1976) Calcium pyrophosphate dihydrate crystal deposition disease — 1975. Arthr. Rheum., 19, 275–85.
McCarty, D. J., Kohn, N. N. and Faires, J. S. (1962) The significance of calcium phosphate crystals in the synovial fluid of arthritis patients: the ‘pseudogout syndrome’. 1. Clinical aspects. Ann. Intern. Med., 56, 711–37.
Merlin, H. E. (1972) Azoospermia caused by colchicine. Fertil. Steril., 23, 180–1.
Mills, R. M. (1971) Severe hypersensitivity reactions associated with allopurinol. J. Am. Med. Assoc., 216, 799–802.
Myers, A. R., Epstein, F. H., Dodge, H. J. and Mikkelsen, W. M. (1968) The relationship of serum uric acid to risk factors in coronary heart disease. Am. J. Med., 45, 520–8.
Nicholls, A., Snaith, M. L. and Scott, J. T. (1973) Effect of oestrogen therapy on plasma and urinary levels of uric acid. Br. Med. J., 1, 449–51.
Nicolaier, A. and Dohrn, M. (1908) Ueber die Wirkung von Chinolincarbonsäure und ihrer Derivate auf die Ausscheidung der Harnsaüre. Deutsch Arc. Klin. Med., xciii, 331–5.
Norcross, B. M. (1963) Treatment of connective tissue diseases with a new non-steroid compound (indomethacin) (Abstract). Arthr. Rheum., 6, 290.
Perd, J. M., Dayton, P. G., Snell, M. M., Yü, T-F. and Gutman, A. B. (1969) Studies of interactions among drugs in man at the renal level: probenecid and sulfinpyrazone. Clin. Pharmacol. Ther., 10, 834–40.
Race, T. F., Paes, I. C. and Falcon, W. W. (1970) Intestinal malabsorption induced by oral colchicine. Am. J. Med. Sci., 259, 32–41.
Reynolds, E. S., Schlant, R. C., Gonick, H. and Dammin, H. C. (1957) Fatal massive necrosis of the liver as a manifestation of hypersensitivity to probenecid. N. Engl. J. Med., 256, 592–6.
Rieselbach, R. E. and Steel, T. H. (1974) Influence of the kidney upon urate haemostasis in health and disease. Am. J. Med., 56, 665–75.
Rieselbach, R. E., Sorensen, L. B., Shelp, W. D. and Steele, T. H. (1970) Diminished renal urate secretion per nephron as a basis for primary gout. Ann. Intern. Med., 73, 359–66.
Rubulis, A., Rubert, M. and Faloon, W. W. (1970) Cholesterol lowering, fecal bile and sterol changes during neomycin and colchicine. J. Clin. Nutr., 23, 1251–9.
Schweitz, M. C., Nashel, D. J. and Alepa, F. P. (1978) Ibuprofen in the treatment of acute gouty arthritis. J. Am. Med. Assoc., 239, 34–5.
Scott, J. T. (1978) Gout, in Copeman’s Textbook of the Rheumatic Diseases (ed J. T. Scott), 5th edn, Churchill Livingstone, Edinburgh, pp. 647–91.
Scott, J. T. (1980) Long-term management of gout and hyperuricaemia. Br. Med. J., 281, 1164–6.
Scott, J. T. and O’Brien, P. K. (1968) Probenecid, nephrotic syndrome and renal failure. Ann. Rheum. Dis., 27, 249–52.
Seegmiller, J. E. and Howell, R. R. (1962) The old and new concepts of acute gouty arthritis. Arthr. Rheum., 5, 616–23.
Seegmiller, J. E., Rosenbloom, R. M. and Kelley, W. N. (1967) An enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis. Science, 155, 1682.
Simmons, F., Feldman, B. and Gerety, D. (1972) Granulomatous hepatitis in a patient receiving allopurinol. Gastroenterology, 62, 101–4.
Skinner, M. and Cohen, A. S. (1969) Calcium pyrophosphate dihydrate crystal deposition disease. Arch. Intern. Med., 123, 636–64.
Sokol, A., Bashner, M. H. and Okun, R. (1967) Nephrotic syndrome caused by probenecid. J. Am. Med. Assoc., 199, 43.
Smyth, C. J. (1970) Indomethacin — its rightful place in treatment. Ann. Intern. Med., 72, 430–2.
Smyth, C. J. (1972) Diagnosis and treatment of gout, in Arthritis and Allied Conditions (eds J. L. Hollander and D. J. McCarty), 8th edn, Lea and Febiger, Philadelphia, pp. 1112–39.
Smyth, C. J., Velayos, E. E. and Amorosa, C. (1963) A method for measuring swelling of hands and feet. II. Influence of new anti-inflammatory drug, indomethacin in acute gout. Acta Rheumatol. Scand., 9, 306.
Sougin-Mibashan, R. and Horwitz, M. (1955) The uricosuric action of ethyl biscoumacetate. Lancet, i, 1191–7.
Stason, W. B., Cannon, P. J., Heinemann, H. O. and Laragh, J. H. (1966) Furosemide. A clinical evaluation of its diuretic action. Circulation, 34, 910–20.
Steele, T. H. (1977) Diuretic-induced hyperuricaemia, in Clinics in Rheumatic Diseases, Vol. 3, No. 1. Crystal-Induced Arthropathies (ed W. N. Kelley), Saunders, London, p. 44.
Straitigos, J. D., Bartosokas, S. K. and Capetanakis, J. (1972) Further experiences of toxic epidermal necrolysis incriminating allopurinol, pyrazolone and derivatives. Br. J. Dermatol., 86, 564–7.
Sturge, R. A., Scott, J. T., Hamilton, E. B. D., Liyanage, S. P., Dixon, A. St. J., Davies, J. and Engler, C. (1977) Multicentre trial of naproxen and phenylbutazone in acute gout. Ann. Rheum. Dis., 36, 80–2.
Talbott, J. H. (1943) Gout, Oxford University Press, London.
Talbott, J. H. (1964) Gout, 2nd edn, Grune and Stratton, New York, p. 206.
Thompson, G. R., Ting, Y. M., Riggs, G. A., Fenn, M. E. and Denning, R. M. (1968) Calcific tendinitis and soft tissue calcification resembling gout. J. Am. Med. Assoc., 203, 464–72.
Tjandramaga, T. B., Cucinell, S. A., Israile, Z. H. et al. (1972) Observations on the disposition of probenecid in patients receiving allopurinol. Pharmacology, 8, 259–72.
Wallace, S. L. (1972) The treatment of gout. Arthr. Rheum., 15, 317–23.
Wallace, S. L. (1975) Colchicine and new antiinflammatory drugs for the treatment of acute gout. Arthr. Rheum., 18, 847–51.
Wallace, S. L. (1977) The treatment of the acute attack of gout, in Clinics in Rheumatic Diseases, Vol. 3, No. 1. Crystal-Induced Arthropathies (ed W. N. Kelley), Saunders, London, p. 138.
Wallace, S. L., Bernstein, D. and Diamond, H. (1967) Diagnostic value of the colchicine therapeutic trial. J. Am. Med. Assoc., 199, 525–8.
Wanasukapunt, S., Lertratanakul, Y. and Rubinstein, H. M. (1976) Effect of fenoprofen calcium on acute gouty arthritis. Arthr. Rheum., 19, 933–8.
Webb, D. I., Chodos, R. B., Mahar, C. Q. and Faloon, W. W. (1968) Mechanism of vitamin B12 malabsorption in patients receiving colchicine. N. Engl. J. Med., 279, 845–50.
Willkens, R. F. and Case, J. B. (1973) Treatment of acute gout with naproxen. Scand. J. Rheumatol. (Suppl.) 2, 69–72.
Willkens, R. F., Case, J. B. and Huix, F. J. (1976) Treatment of acute gout with naproxen. J. Clin. Pharmacol., 16, 363–7.
Wyngaarden, J. B. and Kelley, W. N. (1972) Gout, in The Metabolic Basis of Inherited Disease, 3rd edn (eds J. B. Stanbury, J. B. Wyngaarden and D. S. Fredrickson), McGraw Hill, New York, p. 889.
Wyngaarden, J. B. and Kelley, W. N. (1976) Clinical syndromes associated with hypoxanthine-guanine phosphoribosyltransferase deficiency, in Gout and Hyperuricemia, Grune and Stratton, New York, pp. 309–44.
Yü, T. (1974) Milestones in the treatment of gout. Am. J. Med., 56, 676–85.
Yü, T-F. and Gutman, A. B. (1961) Efficacy of colchicine prophylaxis in gout. Ann. Intern. Med., 55, 179–92.
Yü, T-F., Berger, L. and Gutman, A. B. (1968) Hypoglycemia and uricosuric properties of acetohexamide and hydroxyhexamide. Metabolism, 17, 309–16.
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Moll, J.M.H. (1986). Gout and other crystal-deposition disorders. In: Moll, J.M.H., Bird, H.A., Rushton, A. (eds) Therapeutics in Rheumatology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2883-2_14
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