Abstract
This chapter deals with the control of thyroid function, the formation and secretion of thyroid hormones, their transport in the blood, their action at the cellular level and their metabolism. There are two physiological important thyroid hormones: L triiodothyronine and L thyroxine. L triiodothyronine is the more important hormone at the cellular level, but L thyroxine is the more abundant in the circulation. Thyroxine and triiodothyronine are designated T4 and T3 because they contain 4 and 3 iodine atoms per molecule respectively. Throughout the text, I have used T4 and T3 to indicate serum hormones, and L thyroxine or L triiodothyronine when these compounds are used for treatment. Aspects of iodine intake and excretion are discussed after the formation and metabolism of thyroid hormones.
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McDougall, I.R. (1992). Thyroid physiology. In: Thyroid Disease in Clinical Practice. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2881-8_2
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