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This syndrome is not only serious and well-known, it is also relatively frequent (approximately 1:500 to 1:600 births). For this reason, many parents of mongoloid children come for counseling and wish to know the risk involved in having further children. At the same time, this syndrome is an excellent example for a defect whose roots are so complex that no generally applicable formula for counseling can be given. It again illustrates how very carefully one must examine each individual case if one is to avoid majors errors.
KeywordsGerm Cell Chromosome Aberration Gonadal Dysgenesis Future Child Barr Body
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