Abstract
It has been reported that a raised serum uric acid is related to the development of atherosclerosis, but the direct association between hyperuricemia and atherosclerosis remains uncertain1). Therefore, in gout it seems important to investigate serum lipids which are among the known risk factors for atherosclerosis. In previous studies, some investigators suggested that hyperlipidemia in primary gout was secondary to excessive alcohol intake2) and/or obesity3), while others suggested that hyperlipidemia was a consequence of essential factors in primary gout4).
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References
F.N. Brand, D.L. McGee, W.B. Kannel, J. Stokes III and W.P. Castelli, Hyperuricemia as a risk factor of coronary disease: The Framingham study, Am J Epidemiol 121:11–8 (1985).
T.J. Gibson and R. Grahame, Gout and hyperlipidaemia, Ann Rheum Dis 33:298–303 (1974).
W.J. Fessel, High uric acid as an indicator of cardiovascular disease: independence from obesity, Am J Med 68:401–4 (1980).
S. Jiao, K. Kameda, Y. Matsuzawa and S. Tarui, Hyperlipoproteinaemia in primary gout: Hyperlipoproteinaemic phenotype and influence of alcohol intake and obesity in Japan, Ann Rheum Dis 45:308–13 (1986).
G.M. Kostner, E. Molinari and P. Pichler, Evaluation of a new HDL2/ HDL3 quantitation method based on precipitation with polyethylene glycol, Clin Chim Acta 148:139–47 (1985).
A. Ulreich, G.M. Kostner, K.P. Pfeiffer, P. Sedlmayr and F. Rainer, Serum lipids and lipoproteins in patients with primary gout. Rheumatol Int 5:73–7 (1985).
G.A.A. Fern, J. Lanham, J. Stocks, C. Ritchie, J. Katz and D.J. Galton, The measurement of high density lipoprotein sub-fractions in patients with primary gout using a simple precipitation method, Ann Clin Biochem 22:526–32 (1985).
P. Belfrage, B. Berg, I. Hagerstrand, E.P. Nilsson and H. Tornqvist, Alteration of lipid metabolism in healthy volunteers during long-term ethanol intake, Eur J Clin Invest 7:127–31 (1977).
W.S. Dai, R.E. Laporte and D.L. Horn et al, Alcohol consumption and high density lipoprotein cholesterol concentration among alcoholics, Am J Epidemiol 22:620–7 (1985).
W.P. Castelli, J.T. Doyle and T. Gordon et al, Alcohol and blood lipids; The cooperative lipoprotein phenotyping study, Lancet 11:153–5 (1977).
E. Ford, R. Copper, B. Simmons, S. Katz and R. Patel, Sex differences in high density lipoprotein cholesterol in urban blacks, Am J Epidemiol 127:753–61 (1988).
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© 1991 Springer Science+Business Media New York
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Takahashi, S. et al. (1991). Lipoprotein Metabolism in Primary Gout - Influence of Alcohol Intake and Body Weight. In: Harkness, R.A., Elion, G.B., Zöllner, N. (eds) Purine and Pyrimidine Metabolism in Man VII. Advances in Experimental Medicine and Biology, vol 309A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2638-8_49
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DOI: https://doi.org/10.1007/978-1-4899-2638-8_49
Publisher Name: Springer, Boston, MA
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