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Analysis of Uric Acid Transport in Renal Tubules Using Benzbromarone and Pyrazinamide

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 309A))

Abstract

Four components are said to be involved in the uric acid transport system of the human kidney, but the definite mechanism of uric acid transport has not yet been clarified. We conducted both the benzbromarone (BZB) loading test and the combined pyrazinamide (PZA) and BZB test 1) to quantify the contribution of the four components involved in the renal handling of uric acid, 2) to determine whether BZB selectively inhibits postsecretory reabsorption of uric acid.

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References

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© 1991 Springer Science+Business Media New York

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Moriwaki, Y. et al. (1991). Analysis of Uric Acid Transport in Renal Tubules Using Benzbromarone and Pyrazinamide. In: Harkness, R.A., Elion, G.B., Zöllner, N. (eds) Purine and Pyrimidine Metabolism in Man VII. Advances in Experimental Medicine and Biology, vol 309A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2638-8_34

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  • DOI: https://doi.org/10.1007/978-1-4899-2638-8_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-2640-1

  • Online ISBN: 978-1-4899-2638-8

  • eBook Packages: Springer Book Archive

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