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Measuring Health-Related Quality of Life in Clinical Trials

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Drug Epidemiology and Post-Marketing Surveillance

Part of the book series: NATO ASI Series ((NSSA,volume 224))

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Abstract

During the last decade, the importance of measuring aspects of health status related to patients’ function and subjective experience has become increasingly recognized. The methods available for measuring how patients feel, and how they function, have become more sophisticated. The term “quality of life” has appeared as a label for the measurement of physical and emotional (as opposed to biochemical and physiological) function.1 Of course, quality of life is influenced by many factors other than one’s health (such as one’s income, job satisfaction, social opportunities); what health researchers are interested in is “health-related quality of life” (HRQL). We will use HRQL to refer to the wide variety of subjective experiences (including symptoms, physical function, and emotional function) which are related to health.

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Authors and Affiliations

  1. Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

    Gordon H. Guyatt M.D.

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  1. Gordon H. Guyatt M.D.
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Editor information

Editors and Affiliations

  1. University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Brian L. Strom

  2. University of Verona, Verona, Italy

    Giampaolo Velo

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© 1992 Springer Science+Business Media New York

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Guyatt, G.H. (1992). Measuring Health-Related Quality of Life in Clinical Trials. In: Strom, B.L., Velo, G. (eds) Drug Epidemiology and Post-Marketing Surveillance. NATO ASI Series, vol 224. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2587-9_17

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  • DOI: https://doi.org/10.1007/978-1-4899-2587-9_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-2589-3

  • Online ISBN: 978-1-4899-2587-9

  • eBook Packages: Springer Book Archive

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