Abstract
Ischemic and hypoxic injury to cells and tissues is probably the leading cause of death in human disease. For example, cardiovascular disease frequently produces ischemic and hypoxic injury to heart, brain, bowel, kidney, and liver. In liver, hypoxic injury is associated with congestive centrilobular necrosis, hepatic artery occlusion, and various shock syndromes. Thus, understanding the evolution of alterations in both the structural and functional properties of cells during ischemia may provide new and important information for the development of therapeutic strategies to protect cells from ischemic damage.
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© 1988 Springer Science+Business Media New York
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Herman, B., Nieminen, AL., Gores, G.J., Lemasters, J.J. (1988). Blebbing, Cytosolic Free Calcium, and Mitochondrial Membrane Potential Following Toxic and Anoxic Injury in Hepatocytes. In: Lemasters, J.J., Hackenbrock, C.R., Thurman, R.G., Westerhoff, H.V. (eds) Integration of Mitochondrial Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2551-0_35
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DOI: https://doi.org/10.1007/978-1-4899-2551-0_35
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