Abstract
The H+/e− (protons released externally per electron) and q+/e− (positive charge transfered per electron) stoichiometries of the mitochondrial respiratory complexes are still controversial. Kinetic estimates of the stoichiometries range from 1 to 2 H+/e− (1 to 2 q+/e−) for site 1 (NADH-Q oxidoreductase), (Lawford and Garland, 1973; Di Virgilio and Azzone, 1982); 2H+/e− (lq+/e−) for site 2 (the cytochrome bc 1 complex), although Pietrobon et al. (1981) have suggested that this may be lower at high Δp; and 0 to 2 H+/e− (1 to 3 q+/e−) for site 3 (cytochrome oxidase), (Papa et al. 1983, Wikstrom 1977, Reynafarje et al. 1982).
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Brown, G. (1988). The H+/e− Forces and Stoichiometries of the Mitochondrial Respiratory Chain. In: Lemasters, J.J., Hackenbrock, C.R., Thurman, R.G., Westerhoff, H.V. (eds) Integration of Mitochondrial Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2551-0_17
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