Abstract
Near infrared light (650 – 1100 nm) is capable of penetrating the human scalp and skull (Wan et al. 1981). Hemoglobin and oxyhemoglobin circulating in the cerebrovascular compartment have unique infrared absorption spectra which influence wavelength specific attenuation in this wavelength band (Tamura et al. 1985). The human brain contains 600 to 1000 mg of hemoglobin per 100 grams of tissue; thus, the brain is an excellent organ for in vivo optical spectroscopic (INVOS) measurements of hemoglobin oxygen saturation. Direct and continuous spectroscopic evaluation of cerebral oxygen saturation is possible (McCormick et al. 1991a/b).
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© 1993 Springer Science+Business Media New York
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McCormick, P.W., Stewart, M.C., Lewis, G.D., Zabramski, J.M. (1993). Measurement of Human Hypothermic Cerebral Oxygen Metabolism by Transmission Spectroscopy. In: Dirnagl, U., Villringer, A., Einhäupl, K.M. (eds) Optical Imaging of Brain Function and Metabolism. Advances in Experimental Medicine and Biology, vol 333. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2468-1_4
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DOI: https://doi.org/10.1007/978-1-4899-2468-1_4
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