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Polymeric Materials in Medication pp 11–26Cite as

Tissue/Material Interactions of Biomedical Polymers

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Part of the book series: Polymer Science and Technology ((POLS,volume 32))

Abstract

Of major concern in the development of polymers for medication is the question of the biocompatibility of the polymeric system. We have investigated the biocompatibility of various polymers from the inflammatory response perspective utilizing an in vivo cage system. This cage system permits the quantitive determination of various components of the inflammatory response. Quanitative assays will be presented which can be used to determine the temporal variations in cell function in the inflammatory exudate that interacts with the implanted biomedical polymers or drug-polymer delivery systems. In addition, correlative, comparative, and quantitative information on the release characteristics and cellular response, adhesion and activation, that is the biocompatibility, of polymeric systems also will be presented.

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Author information

Authors and Affiliations

  1. Departments of Macromolecular Science and Pathology, Case Western Reserve University, Cleveland, OH, 44106, USA

    R. E. Marchant & J. M. Anderson

Authors
  1. R. E. Marchant
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  2. J. M. Anderson
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Editor information

Editors and Affiliations

  1. Youngstown State University, Youngstown, Ohio, USA

    Charles G. Gebelein

  2. Florida Atlantic University, Boca Raton, Florida, USA

    Charles E. Carraher Jr.

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© 1985 Springer Science+Business Media New York

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Marchant, R.E., Anderson, J.M. (1985). Tissue/Material Interactions of Biomedical Polymers. In: Gebelein, C.G., Carraher, C.E. (eds) Polymeric Materials in Medication. Polymer Science and Technology, vol 32. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2245-8_2

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  • DOI: https://doi.org/10.1007/978-1-4899-2245-8_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-2247-2

  • Online ISBN: 978-1-4899-2245-8

  • eBook Packages: Springer Book Archive

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