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Effects of Insecticides on Nervous Conduction and Synaptic Transmission

  • Chapter
Insecticide Biochemistry and Physiology

Abstract

The intoxication of an organism with insecticide involves a variety of steps and reactions (Narahashi, 1971a). The uptake of insecticide is the first step to occur, and a number of factors such as lipid solubility and vapor pressure of insecticide are related to this process (Chapter 1). The insecticide that has entered the body is then transported to various organs and may undergo a variety of biotransformations in which it is either converted into a more potent compound or degraded to one which is relatively nontoxic (Chapters 2, 4, and 5). The active form of the insecticide eventually reaches its target site and exerts effects characteristic of the insecticide and the tissue concerned.

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  1. Department of Physiology and Pharmacology, Duke University Medical Center, Durham, North Carolina, USA

    Toshio Narahashi

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  1. Toshio Narahashi
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  1. Cornell University, Ithaca, New York, USA

    C. F. Wilkinson

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Narahashi, T. (1976). Effects of Insecticides on Nervous Conduction and Synaptic Transmission. In: Wilkinson, C.F. (eds) Insecticide Biochemistry and Physiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2212-0_9

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  • DOI: https://doi.org/10.1007/978-1-4899-2212-0_9

  • Publisher Name: Springer, Boston, MA

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