Summary
The tumor markers; CEA, CA 19-9, CA 125, CA 15-3 levels in effusions caused by some common malignant tumors, such as breast, gastrointestinal tract and ovarian cancers were compared to the serum levels of the same group of patients. Thirty three patients were included in the study group. Comparison with benign effusions (12 patients) was also carried out. Corresponding tumor markers designated for each tumor type were analyzed besides CEA which was measured in all patients. Although we got more positive results in malign effusions than the sera, this difference was not statistically significant (p>0.05). But mean values of tumor markers were found to be statistically higher in malign effusions when they are compared to the sera of the same patients and to the benign effusions of control group (p < 0.05). As a result, determination of tumor markers in the effusions is more sensitive than in the sera and this method is also useful for differential diagnosis of benign and malign effusions.
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© 1993 Springer Science+Business Media New York
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Gullu, I. et al. (1993). Tumor Markers in Effusions: A Comparative Study of Tumor Marker Levels in Sera and Effusions. In: Travis, C.C. (eds) Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants. NATO ASI Series, vol 250. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2052-2_25
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DOI: https://doi.org/10.1007/978-1-4899-2052-2_25
Publisher Name: Springer, Boston, MA
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