Skip to main content

Part of the book series: NATO ASI Series ((NSSA,volume 250))

  • 78 Accesses

Abstract

In 1980 the participants of a seminar organized by CEC, NIOSH and OSHA (Berlin et al., 1984) agreed upon the following definitions:

  1. 1.

    Monitoring (in preventive health care) is “a systematic continuous or repetitive health related activity, designed to lead if necessary to corrective action”.

  2. 2.

    Biological monitoring (BM) is “the measurement and assessment of workplace agents or their metabolites either in tissues, secreta excreta or any combination of these to evaluate exposure and health risk compared to an appropriate reference”.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • ACGIH, 1991–1992, Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices.

    Google Scholar 

  • Berlin A., Yodaiken R.E., Henman B.A., 1984, “Assessment of toxic agents at the workplace. Roles of ambient and biological monitoring”, Nijhoff, Boston, The Hague, Wordrecht, Lancaster.

    Google Scholar 

  • Brugnone F., De Rosa E., Perbellini L., Bartolucci G.B., 1986, Toluene concentrations in the blood and alveolar air of workers during the workshift and the morning after, Brit. J Ind Med. 43:56.

    CAS  Google Scholar 

  • CEC, 1983, “Human Biological Monitoring of Industrial Chemicals Series”, Alessio L., Berlin A., Roi R., Boni M. ed. Office for Official Publications of the European Communities, Luxemburg.

    Google Scholar 

  • Cornish H.H., Ling B.P., Barth M.L., 1974, Phenobarbital and organic solvent toxicity, Am Ind Hyg Assoc J. 34:487.

    Google Scholar 

  • David A., Flek J., Frantik E., Gut I., Sedivec V., 1979,Influence of phenobarbital on xylene metabolism, Int Arch Occup Environ Health. 44:117.

    Article  PubMed  CAS  Google Scholar 

  • DFG, 1990, Maximale Arbeitsplatzkonzentrationen und Biologische Arbeitsstofftoleranzwerte.

    Google Scholar 

  • Dutkiewicz T., 1963, Quantitative exposure test for benzene, in: International Congress Series No 62, Int.Congr.Occup. Health, Excerpta Medica.

    Google Scholar 

  • Engstrom K., Husman K., Rantanen J., 1976, Urinary mandelic acid concentration after occupational exposure to styreneand its use as a biological exposure test, Scand J Work Environ Health. 2:21.

    Article  PubMed  CAS  Google Scholar 

  • Engström K., Husman K., Riihimaki V., 1977,Percutaneous absorption of m-xylene in man, Int Arch Occup Environ Health. 39:181.

    Article  PubMed  Google Scholar 

  • Engström K., Riihimaki V., Laine A., 1984, Urinary disposition of ethylbenzene and m-xylene in man following separate and combined exposure, lnt Arch Occup Environ Health. 54:355.

    Article  Google Scholar 

  • Jakubowski M., Kostrzewski P., 1989, Excretion of methyl- benzoic acid in urine as a result of single and combined exposure to m-xylene, Polish J Occup Med. 2:238.

    CAS  Google Scholar 

  • Jongeneelen F.J., Auzion R.B.M., Scheepers P.T.J., Bos R.P., Henderson P.Th., Nijenhuijs E.H., Veenstra S.J., Brouns R.M.E., Winkers A., 1988, 1-Hydroxypyrene in urine as a biological indicator of exposure to polycyclic aromatic hydrocarbons in several work environments, Ann Occup Hyg. 32:35.

    Article  PubMed  CAS  Google Scholar 

  • Kostrzewski P., Jakubowski M., 1985, Application of determinations of volatiles in capillary blood samples for evaluation of industrial exposure: tetrachloroethylene, Ann Am Conf Ind Hyg. 12:269.

    CAS  Google Scholar 

  • Kostrzewski P., Piotrowski J.K., 1991, Toluene determination in capillary blood as a biological indicator of exposure to low levels of toluene, Pol J Occup Med Environ Health, 3:249.

    Google Scholar 

  • Liira J., Riihimaki V., Engstrom K., Pfaffli P.,1988,Coexposure of man to m-xylene and methyl ethyl ketone ,Scand J Work Environ Health. 14:322.

    Article  PubMed  CAS  Google Scholar 

  • Lundberg I., Sollenberg J., 1986, Correlation of xylene exposure and methylhippuric acid excretion in urine among paint industrial workers, Scand J Work Environ Health. 12:149.

    Article  PubMed  CAS  Google Scholar 

  • Ogata M., Tomokuni K., Takatsuka Y.,1970, Urinary excretion of hippuric acid and m- or p-xylene as atest of exposure, Brit J Ind Med, 27:43.

    CAS  Google Scholar 

  • Ohtsui H., Ikeda M., 1971, The metabolism of styrene in the rat and the stimulatory effect of phenobarbital, Toxicol Appl Pharmacol. 18:321.

    Article  Google Scholar 

  • Piotrowski J.K., 1977, “Exposure Test for Organic Compounds in Industrial Toxicology”, U.S. Department of Health, Education and Welfare, NIOSH, Cincinnati.

    Google Scholar 

  • Phillips D.L., Smith A.B., Burse V.W., Steele G.K., Needhan L.L., Hannon W.H., 1989, Half-life of polychlorinated biophenyls in occupationally exposed workers, Arch Environ Health. 44:351.

    Article  PubMed  CAS  Google Scholar 

  • Riihimaki V., Savolainen K., Pfaffli P., Pekari K., Sippel H.W., Laine A., 1982, Metabolic interaction between m-xylene and ethanol, Arch Toxicol. 49:253.

    Article  PubMed  CAS  Google Scholar 

  • Robertson P.Jr., White E.L., Bus J.S.,1989,Effects of methyl ethyl ketone pretreatment on hepatic mixed — function oxidase activity and on in vivo metabolism of n-hexane, Xenobiotica. 19:721.

    Article  PubMed  Google Scholar 

  • Roush G.J., Ott G., 1977, A study of benzene exposure versus urinary phenol levels, Am Ind Hyg Assoc J. 38:67.

    Article  PubMed  CAS  Google Scholar 

  • Schulte P., Halperin W., Herrick M., Connally B.,1987,The current focus on biological monitoring in: “Occupational and Environmental Chemical Hazards: Cellular and Biochemical Indices for Monitoring Toxicity”, V. Foa, E.A. Emmett, M. Maroni ed., Ellis Horwoad Ltd. Chichester, England.

    Google Scholar 

  • Sedivec V., Flek J., 1976, Exposure test for xylenes, loi Arch Occup Environ Health. 37:219.

    Article  CAS  Google Scholar 

  • Senczuk W., Orlowski J., 1978, Absorption rate of m-xylene vapours through the respiratory tract and excretion of m-methylhippuric acid in urine, Brit J Ind Med. 35:50.

    CAS  Google Scholar 

  • Sherwood R.J., 1972, Evaluation of exposure to benzene vapour during the loading of petrol, Brit J lnd Med. 29:65.

    CAS  Google Scholar 

  • Walkley J.E., Pagnotto L.D., Elkins H.B., 1961, The measurement of phenol in urine as an index of benzene exposure, Amer lnd Hyg Assoc J. 22:362.

    Article  CAS  Google Scholar 

  • WHO, 1981, “Recommended Health-Based Limits in Occupational Exposure to Selected Organic Solvents”. Tech Rep Ser 664,WHO Geneva.

    Google Scholar 

  • Zielhuis R.I., Henderson P.Th., 1986, Definitions of monitoring activities and their relevance for the practice of occupational health, Int Arch Occup Environ Health. 57:249.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer Science+Business Media New York

About this chapter

Cite this chapter

Jakubowski, M. (1993). Biological Monitoring of Exposure to Organic Compounds. In: Travis, C.C. (eds) Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants. NATO ASI Series, vol 250. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2052-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-2052-2_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-2054-6

  • Online ISBN: 978-1-4899-2052-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics