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Medical Applications

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Infrared Absorbing Dyes

Part of the book series: Topics in Applied Chemistry ((TAPP))

Abstract

Plants and bacteria capture light in the visible and near-infrared region by absorption using various chlorophylls, while photosynthetic bacteria utilize bacteriochlorophylls. The resulting energy of the photoexcited state is ultimately utilized to execute a series of reductions of carbon dioxide and the liberation of oxygen from water.1 Other photoexcited-state species, which are derived from compounds that absorb in the near-UV region, are utilized by plants as a means of protection against deprivation by fungi or bacteria or ingestion by animals or insects.2,3 These near-UV and visible absorbing compounds act as photocatalysts for the conversion of triplet state oxygen to toxic, singlet state oxygen4 (Figure 1, Type II) or may react in the absence of oxygen by photoinitiated electron transfer in the presence of a biological enzymatic system5 (Figure 1, Type I), while the psoralens can cause DNA cross-linking.6 A form of the latter has been approved as a phototherapy for a form of T-cell lymphoma.7 This review will concentrate on Type I and Type II toxic modalities with compounds that absorb on the edge of the visible region and into the near-infrared region.

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Authors and Affiliations

  1. Department of Chemistry, University of British Columbia, Vancouver, British Columbia, V6T 1Y6, Canada

    Ethan Sternberg & David Dolphin

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  1. Ethan Sternberg
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  2. David Dolphin
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  1. Department of Applied Chemistry, College of Engineering, University of Osaka Prefecture, Sakai, Osaka, 591, Japan

    Masaru Matsuoka

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Sternberg, E., Dolphin, D. (1990). Medical Applications. In: Matsuoka, M. (eds) Infrared Absorbing Dyes. Topics in Applied Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2046-1_15

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  • DOI: https://doi.org/10.1007/978-1-4899-2046-1_15

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