Abstract
Radioimmunoassay revolutionized the capability of endocrinologists and clinical chemists to quickly and inexpensively analyze biological chemicals that occur naturally in small quantities. Only a few problems exist with RIAs: i) RIAs require the use of radioisotopes. These compounds are expensive and their use requires special training and handling, ii) The turn-around time for RIAs can range from several hours to several days. RIA is not very practical for monitoring biological compounds or changes in concentration as a function of time, because of the slow turn-around time of these assays. A technique that would allow on-line measurements would be extremely useful.
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Connell, G.R., Sanders, K.M. (1987). Electroimmunoassay of PGE2: An Antibody-Sensitive Electrode Based Competitive Protein-Binding Assay. In: Ngo, T.T. (eds) Electrochemical Sensors in Immunological Analysis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1974-8_3
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DOI: https://doi.org/10.1007/978-1-4899-1974-8_3
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