Abstract
Molecular recognition and signal transduction are amalgamated in a biosensor in various manners. Molecular recognition is responsible for the selectivity of a biosensor. Many a biomolecule has an intrinsic nature to recognize its counterpart; an enzyme recognizes its substrate, and an antibody selectively binds its corresponding antigen. These biomolecules have been utilized as sensor material to develop such biosensors as an enzyme sensor and an immunosensor (Aizawa et al., 1983).
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References
Aizawa, M., 1983, Molecular recognition and chemical amplification of biosensors, in “Chemical Sensors,” Seiyama T., et al., eds., Kodansha-Elsevier, Tokyo, p.683.
Beers, R. F., Jr., and Sizer, I. W., 1952, A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase, J. Biol. Chem., 195: 133.
Green, N.M., 1965, A spectrophotometric assay for avidin and biotin based on binding of dyes by avidin, Biochem. J., 94: 23c.
Green, N.M., 1966, Thermodynamics of the binding of biotin and some analogues by avidin, Biochem. J., 101: 774.
Green, N.M., 1970, Purification of avidin, in: “Methods in Enzymology, vol.18 Part A,” McCormich, D. B., and Wright, L. D., eds., Academic Press, New York, p.414.
Ikariyama, Y. and Aizawa, M., 1982, Bioaffinity sensor (Determination of Thyroxine), Proc. 2nd Sensor Symp., p.97.
Ikariyama, Y. and Aizawa, M., 1983, Bioaffinity sensor for insulin with luminescence detection, Proc. 3rd Sensor Symp., p.17.
Ikariyama, Y. and Aizawa, M., 1985, Sensitive Bioaffinity sensor with metastable molecular complex receptor and enzyme amplifier, Anal.Chem., 57: 496.
Schultz, J. S., and Sims, G., 1979, Affinity sensors for individual metabolites, Biotechnol. Bioeng. Symp., 9: 65.
Yamakawa, T., ed., 1980, “Data Book of Biochemistry vol.1,” Tokyo Kagaku Dojin, Tokyo, p.94.
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© 1987 Springer Science+Business Media New York
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Aizawa, M. (1987). Bioaffinity Electrochemical Sensor with Preformed Metastable Ligand-Receptor Complex. In: Ngo, T.T. (eds) Electrochemical Sensors in Immunological Analysis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1974-8_20
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DOI: https://doi.org/10.1007/978-1-4899-1974-8_20
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-1976-2
Online ISBN: 978-1-4899-1974-8
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