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Accelerator Mass Spectrometry as a Bioanalytical Tool for Nutritional Research

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Mathematical Modeling in Experimental Nutrition

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 445))

Abstract

Accelerator Mass Spectrometry is a mass spectrometric method of detecting long-lived radioisotopes without regard to their decay products or half-life. The technique is normally applied to geochronology, but is also available for bioanalytical tracing. AMS detects isotope concentrations to parts per quadrillion, quantifying labeled biochemicals to attomole levels in milligram-sized samples. Its advantages over non-isotopic and stable isotope labeling methods are reviewed and examples of analytical integrity, sensitivity, specificity, and applicability are provided.

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Author information

Authors and Affiliations

  1. Center for Accelerator Mass Spectrometry, Lawrence Livermore National Laboratory, 7000 East Avenue, L-397, Livermore, CA, 94551, USA

    John S. Vogel

  2. Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, 7000 East Avenue, L-397, Livermore, CA, 94551, USA

    Kenneth W. Turteltaub

Authors
  1. John S. Vogel
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  2. Kenneth W. Turteltaub
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Editor information

Editors and Affiliations

  1. University of California at Davis, Davis, California, USA

    Andrew J. Clifford  & Hans-Georg Müller  & 

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© 1998 Springer Science+Business Media New York

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Vogel, J.S., Turteltaub, K.W. (1998). Accelerator Mass Spectrometry as a Bioanalytical Tool for Nutritional Research. In: Clifford, A.J., Müller, HG. (eds) Mathematical Modeling in Experimental Nutrition. Advances in Experimental Medicine and Biology, vol 445. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1959-5_25

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  • DOI: https://doi.org/10.1007/978-1-4899-1959-5_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1961-8

  • Online ISBN: 978-1-4899-1959-5

  • eBook Packages: Springer Book Archive

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