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Catalase, Glutathione Peroxidase, Superoxide Dismutase, and Cytochrome P-450

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Handbook of Neurochemistry

Abstract

Catalase and glutathione peroxidase (GSH peroxidase) play significant roles in protecting cells against the toxic action of peroxides. Until relatively recently, research interest in these two enzymes in neural tissue had been quite minimal. The levels of enzymatic activity seen in brain are very low, accounting for only several percent of that seen in liver. Studies with liver and erythrocytes, two cell types with high enzymatic activity, have tended to dominate experimental concerns with peroxides and their disposition.

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Authors and Affiliations

  1. Department of Neurology, Mount Sinai School of Medicine of the City University of New York, New York, New York, 10029, USA

    Gerald Cohen

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  1. Gerald Cohen
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  1. Center for Neurochemistry, Rockland Research Institute, Wards Island, New York, New York, 10035, USA

    Abel Lajtha

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Cohen, G. (1983). Catalase, Glutathione Peroxidase, Superoxide Dismutase, and Cytochrome P-450. In: Lajtha, A. (eds) Handbook of Neurochemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1881-9_13

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  • DOI: https://doi.org/10.1007/978-1-4899-1881-9_13

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