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Neuropeptidases

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Handbook of Neurochemistry

Abstract

Neuropeptidases can be defined as peptidases that are active in the brain or as enzymes that degrade neuropeptides, peptide hormones, or neuromodulators found in the brain. Turnover of neuropeptides (synthesis and degradation) is extremely rapid, and the high level of degrading activity results in their having low levels in the brain. Peptidases in the brain are involved in general metabolism of peptides and, in addition, possibly participate in neurotransmission. In this chapter, we concentrate on the peptidases involved in neuropeptide degradation.

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Authors and Affiliations

  1. Center for Neurochemistry, Rockland Research Institute, Wards Island, New York, New York, 10035, USA

    Koon-Sea Hui & Abel Lajtha

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  1. Koon-Sea Hui
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  2. Abel Lajtha
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  1. Center for Neurochemistry, Rockland Research Institute, Wards Island, New York, New York, 10035, USA

    Abel Lajtha

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Hui, KS., Lajtha, A. (1983). Neuropeptidases. In: Lajtha, A. (eds) Handbook of Neurochemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1881-9_1

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  • DOI: https://doi.org/10.1007/978-1-4899-1881-9_1

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