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Intracellular Second Messengers

  • Stephen J. H. Ashcroft
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 426)

Abstract

In the β-cell, the effects of extracellular signals are mediated by changes of concentration of intracellular second messengers. Complex interrelationships among the signalling pathways determine the rate of insulin release and also can modulate the rate of insulin biosynthesis. This short overview summarises some key properties of the known second messenger systems of the β-cell. References cited are, where possible, to reviews in order to keep the reference list to a reasonable size.

Keywords

Insulin Secretion Pancreatic Islet Insulin Release Human Islet Nutrient Regulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Stephen J. H. Ashcroft
    • 1
  1. 1.Nuffield Department of Clinical BiochemistryJohn Radcliffe HospitalHeadington, OxfordUK

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