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Activation of Peritoneal Macrophages During the Prediabetic Phase in Low-Dose Streptozotocin-Treated Mice

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Physiology and Pathophysiology of the Islets of Langerhans

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 426))

Abstract

It has been shown recently that islet cell lysis induced by C. parvum-activated macrophages is mediated by NO since cell destruction can be counteracted by NO synthase inhibitors [1]. However, evidence concerning the activation state of macrophages and the effector molecules that mediate islet destruction in experimental immune diabetes is lacking.

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References

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© 1997 Springer Science+Business Media New York

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Andrade, J., Conde, M., Sobrino, F., Bedoya, F.J. (1997). Activation of Peritoneal Macrophages During the Prediabetic Phase in Low-Dose Streptozotocin-Treated Mice. In: Soria, B. (eds) Physiology and Pathophysiology of the Islets of Langerhans. Advances in Experimental Medicine and Biology, vol 426. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1819-2_45

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  • DOI: https://doi.org/10.1007/978-1-4899-1819-2_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1821-5

  • Online ISBN: 978-1-4899-1819-2

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