Physiological Behavior of Functional Subpopulations of Single Pancreatic β-Cells

  • Marcia Hiriart
  • Ma. Teresa Martinez
  • Ma. del Carmen Ramírez-Medeles
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 426)


Single pancreatic β-cells are heterogeneous, the following are observations of β-cell variability: insulin content and biosynthesis of individual β-cells (Pipeleers, 1987; Schuit et al., 1988), glucose transport (Tominaga et al., 1986), electrical activity (Dean and Mattews, 1970; Ashcroft et al., 1987) and insulin secretion (Salomon and Meda, 1986; Hiriart and Matteson, 1988; Hiriart and Ramirez-Medeles, 1991; Van Schravendijk et al., 1992).


Insulin Secretion Secretion Rate Plaque Area Insulin Secretion Rate Medium Secretion 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Marcia Hiriart
    • 1
  • Ma. Teresa Martinez
    • 1
  • Ma. del Carmen Ramírez-Medeles
    • 2
  1. 1.Department of Bioenergetics, Instituto de Fisiología CelularUniversidad Nacional Autónoma de MéxicoMexico
  2. 2.Department of Biological SystemsUniversidad Autónoma MetropolitanaXochimilco, D.F.Mexico

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