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Extracellular Messages for Pancreatic B-Cells

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Physiology and Pathophysiology of the Islets of Langerhans

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 426))

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Abstract

Insulin secretion from pancreatic B-cells is subject to fine regulation by a variety of extracellular messages, which include nutrients of dietary origin, physiological messengers of neural and hormonal origins, and pharmacological agents. In this article, I will briefly review the major, classical messages of each type, and then focus on new studies on the substances that have recently been discovered or developed. Particular attention will be paid on their origin, action mechanisms in pancreatic B-cells, and potential physiological or pharmacological significance in the regulation of insulin release.

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Authors and Affiliations

  1. Department of Physiology, Kagoshima University School of Medicine, 8-35-1 Sakuragaoka, Kagoshima 890, Japan

    Toshihiko Yada

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  1. Toshihiko Yada
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Editors and Affiliations

  1. Miguel Hernandez University, Alicante, Spain

    Bernat Soria

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© 1997 Springer Science+Business Media New York

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Yada, T. (1997). Extracellular Messages for Pancreatic B-Cells. In: Soria, B. (eds) Physiology and Pathophysiology of the Islets of Langerhans. Advances in Experimental Medicine and Biology, vol 426. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1819-2_14

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  • DOI: https://doi.org/10.1007/978-1-4899-1819-2_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1821-5

  • Online ISBN: 978-1-4899-1819-2

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