Abstract
The lipid composition of fungi has been well studied. It is generally accepted that C16 and C18 chain length fatty acids (FAs) are the major FAs in fungi. Fungi are also characterised by the presence of both the ω3 and ω6 series of polyunsaturated FAs (PUFAs). The ω3 series include the PUFAs i. e. α-linolenic acid (18: 3, ω3) while the ω6 series include mainly linoleic acid (18: 2, ω6), γ-linolenic acid (18: 3, ω6), di homo γ-linolenic acid (20: 3, ω6) and arachidonic acid (20: 4, ω6). Both the ω3 and ω6 PUFAs are derived from 18: 2 ω6 by the participation of various desaturase and elongase enzymes (Smit, 1993; Van der Westhuizen, 1994).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Kendrick, B., 1992, The Fifth Kingdom, Mycologue Publications, Ontario.
Kock, J.L.F., Coetzee, D.J., Van Dyk, M.S., Truscott, M., Cloete, F.G., Van Wyk, V., and Augustyn, O.P.H., 1991, Evidence for pharmacologically active prostaglandins in yeasts. S. Afr. J. Sci. 87: 73–76.
Kock, J.L.F., Jansen van Vuuren, D., Botha, A., Van Dyk, M.S., Coetzee, D.J., Botes, P.J., Shaw, N., Friend, J., Ratledge, C., Roberts, A.D., and Nigam, S., 1997, The production of biologically active 3-hydroxy-5,8,11,14-eiosatetraenoic acid (3-HETE) and linoleic acid metabolites by Dipodascopsis. System. Appl. Microbiol. 20: 39–49.
Smit, M.S., 1993, The turnover of exogenous arachidonic acid by the yeast Dipodascopsis uninucleata. Ph.D. Thesis. Department of Microbiology and Biochemistry, University of the Orange Free State, Bloemfontein, South Africa.
Van der Westhuizen, J.P.J., 1994, The distribution of the ω3 and ω6 series of cellular long-chain fatty acids in fungi associated with disease. Ph.D. Thesis. Department of Microbiology and Biochemistry, University of the Orange Free State, Bloemfontein, South Africa.
Van Dyk, M.S., Kock, J.L.F., Coetzee, D.J., Augustyn, O.P.H., and Nigam, S., 1991, Isolation of a novel arachidonic acid metabolite 3-hydroxy 5,8,11,14-eicosatetraenoic acid (3-HETE) from the yeast Dipodascopsis uninucleata UOFS-Y128. FEBS Lett. 283: 195–198.
Venter, P., Kock, J.L.F., Botha, A., Coetzee, D.J., P.J. Botes, and Nigam, S., 1997, The production of 3-hydroxy fatty acids by the yeast Dipodascopsis uninucleata. (manuscript in preparation).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Springer Science+Business Media New York
About this chapter
Cite this chapter
Lodewyk, J. et al. (1997). The Production of Biologically Active Eicosanoids by Yeasts. In: Sinzinger, H., Samuelsson, B., Vane, J.R., Paoletti, R., Ramwell, P., Wong, P.YK. (eds) Recent Advances in Prostaglandin, Thromboxane, and Leukotriene Research. Advances in Experimental Medicine and Biology, vol 433. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1810-9_46
Download citation
DOI: https://doi.org/10.1007/978-1-4899-1810-9_46
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-1812-3
Online ISBN: 978-1-4899-1810-9
eBook Packages: Springer Book Archive