Abstract
Genetic analysis of microorganisms has been valuable in two ways. Information about genetic mechanisms which are fundamental to all organisms, such as the chemical structure of the genetic material and the mechanism of mutation, has been obtained. In addition to their unique and fascinating biological and chemical properties, the microorganisms are important in health and disease, in nutrient cycles in nature, and in industrial processes. The enteric group of Gram-negative bacteria, which includes genera such as Salmonella, Escherichia, and Shigella has been a favorite subject of study, for the following reasons: Their growth rate is rapid, with a generation time as low as 30 minutes or less. Cell division produces single cells, most of which are uninucleate, at least in stationary phase. The species are facultative aerobes and usually grow on a defined medium and on a wide range of carbon and energy sources. Colonies which can be readily observed and enumerated are formed on agar medium.
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Levinthal, M., Sanderson, K.E. (1974). Salmonella. In: King, R.C. (eds) Bacteria, Bacteriophages, and Fungi. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1710-2_13
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