Skip to main content
SpringerLink
Log in

Methodological and Ethical Issues in Alcohol Research

  • Chapter
Recent Developments in Alcoholism

Part of the book series: Recent Developments in Alcoholism ((RDIA,volume 7))

Abstract

A commitment to scientific endeavors is an important part of the healing mission and public apprehension derived from this type, of activity should not inhibit efforts to gain new knowledge. This imperative, however, does not dismiss the responsibility of every investigator to be deeply concerned with the morality of research activities and its impact on the health and welfare of the persons who participate as subjects. It was therefore considered important to review in this chapter some of the ethical principles that guide research, and in particular those relevant to research paradigms that incorporate the administration of alcohol (ethanol) as one of the variables.

“Everything has been said but it is necessary to be said again because some have not listened.” >—André Gide

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Tranoy KE: Is there a universal research ethics? in Berg K, Tranoy KE (eds): Research Ethics. New York, Alan R. Liss, 1983.

    Google Scholar 

  2. Armor DJ, Polich JM, Stambul HB: Alcoholism and Treatment. Santa Monica, CA, Rand Corporation, 1976.

    Google Scholar 

  3. Hingson R, Scotch N, Golman E: Impact of the Rand Report on alcoholism treatment personnel and Boston residents. J Stud Alcohol 38: 2065–2076, 1977.

    PubMed  CAS  Google Scholar 

  4. Carrol RS, Miller A, Ross B, Simpson G: Research as impetus to improved treatment. Arch Gen Psychiatry 37: 377–380, 1980.

    Article  Google Scholar 

  5. Beecher HK: Research and the Individual: Human Studies. Boston, Little, Brown, 1970.

    Google Scholar 

  6. Gibson W: The cost of not doing research. J Am Med Assoc 244: 1817–1819, 1980.

    Article  CAS  Google Scholar 

  7. Edwards G: Comments on the alcoholic game. Q J Stud Alcohol 30: 948–951, 1969.

    Google Scholar 

  8. Williams HL, Salamy A: Alcohol and sleep, in Kissin B, Beigleiter H (eds): Biology of Alcoholism, Vol 2, New York, Plenum Press, 1978, pp 435–483.

    Google Scholar 

  9. Lieber C: Metabolic Aspects of Alcoholism. London, William Clowes and Sons, Colchester and Beccles, 1977.

    Google Scholar 

  10. Schukit M, Ting-Kai L, Clonninger R, Dietrich R: Conference: Genetics of alcoholism. Alcohol Clin Exp Res 9: 475–492, 1985.

    Article  Google Scholar 

  11. Schukit M: Genetics and the risk for alcoholism. J Am Med Assoc 254: 2614–2617, 1985.

    Article  Google Scholar 

  12. Lawson DM, Nathan PE, Lipscomb TR: Guidelines for the administration of alcohol to human subjects. J Stud Alcohol 41: 871–881, 1980.

    PubMed  CAS  Google Scholar 

  13. Mendelson JH: Experimentally induced chronic intoxication and withdrawal in alcoholics. Q J Stud Alcohol suppl. 2: 117–126, 1964.

    Google Scholar 

  14. Mendelson JH, La Dou J: Experimentally induced chronic intoxication and withdrawal in alcoholics. Q J Stud Alcohol suppl 2: 40–52, 1964.

    Google Scholar 

  15. Lovibond SH, Caddy G: Discriminated aversive control in the moderation of alcoholic’s drinking behavior. Behav Ther 1: 437–444, 1970.

    Article  Google Scholar 

  16. Nathan PE, Titler NA, Lowenstam LM, Solomon P, Ross AM: Behavioral analysis of chronic alcoholism. Arch Gen Psychiatry 22: 419–430, 1970.

    Article  PubMed  CAS  Google Scholar 

  17. Nathan PE, Goldman MS: Alcoholism and alcoholics: Behavioral approach. Trans NY Acad Sci 34: 602–627, 1972.

    Article  CAS  Google Scholar 

  18. Gottheil E, Alterman AI, Skoloda TF, Murphy B: Alcoholics’ patterns of controlled drinking. Am J Psychiatry 130: 418–422, 1973.

    PubMed  CAS  Google Scholar 

  19. Paredes A, Hood WR, Seymour H, Gollob M: Loss of control in alcoholism: An investigation of the hypothesis, with experimental findings. Q J Stud Alcohol 34: 1146–1161, 1973.

    PubMed  CAS  Google Scholar 

  20. Sobell MB, Sobell LC: Individualized behavior therapy for alcoholics. Behav Ther 4: 49–72, 1973.

    Article  Google Scholar 

  21. Griffiths R, Bigelow G, Liebson I: Suppression of ethanol self administration by contingent time-out from social interaction. Behav Res Ther 12: 324–327, 1974.

    Google Scholar 

  22. Paredes A, Jones MB, Gregory D: Blood alcohol discrimination training with alcoholics, in Seixas FA (ed): Currents in Alcoholism, Vol 2. New York, Grune and Stratton, 1977.

    Google Scholar 

  23. Miller WR: Controlled drinking: a history and a critical review. J Stud Alcohol 44: 68–83, 1983.

    PubMed  CAS  Google Scholar 

  24. Vogel-Sprott M: Self evaluation of performance and the ability to discriminate blood alcohol concentrations. J Stud Alcohol 36: 1–10, 1975.

    PubMed  CAS  Google Scholar 

  25. Huber H, Karlin R, Nathan OE: Blood alcohol discrimination by nonalcoholics (The role of internal and external cues). J Stud Alcohol 37: 27–39, 1976.

    PubMed  CAS  Google Scholar 

  26. Langslet LR: Inaugural statement, in Berg K, Tranoy K (eds): Research Ethics. New York, Alan R. Liss, 1983.

    Google Scholar 

  27. Melmon K, Grossmanm M, Morrison RC Jr: Emerging assets and liabilities of a committee on human welfare and experimentation. N Engl J Med 282: 427–434, 1970.

    Article  PubMed  CAS  Google Scholar 

  28. Bower RT, de Gasparis P: Ethics in Social Research. New York, Praeger, 1978.

    Google Scholar 

  29. Cole J: Research barriers in psychopharmacology. Am J Psychiatry 134: 896–898, 1977.

    PubMed  CAS  Google Scholar 

  30. Gray B, Cooke RA, Tanembaum AS: Research involving human subjects. Science 201: 1094–1101, 1978.

    Article  PubMed  CAS  Google Scholar 

  31. Platt R: Ethical problems in medical procedures, in Ciba Foundation Symposium Ethics in Medical Progress. Boston, Little, Brown, 1966.

    Google Scholar 

  32. Gray BH: The functions of human subject committees. Am J Psychiatry 134: 907–910, 1977.

    PubMed  CAS  Google Scholar 

  33. Berg K, Tranoy KE: Research Ethics. New York, Alan R. Liss, 1983.

    Google Scholar 

  34. Pendery ML, Maltzman IM, West LJ: Controlled drinking by alcoholics? New findings and a reevaluation of a major affirmative study. Science 217: 169–175, 1982.

    Article  PubMed  CAS  Google Scholar 

  35. Roizan, R: The great controlled drinking controversy, in Galanter M (ed): Recent Developments in Alcoholism, Vol 5, New York, Plenum Press, 1987, pp 245–279.

    Chapter  Google Scholar 

  36. Engler R, Correll J, Friedman PJ, Kitcher PS, Peters RM: Misrepresentation and responsibility in medical research. N Engl J Med 317: 1383–1389, 1987.

    Article  PubMed  CAS  Google Scholar 

  37. Doob AN, Warwick OH: Report of the Committee of Enquiry into Allegations Concerning Drs. Linda and Mark Sobell. Toronto, Alcoholism and Drug Addiction Foundation, 1982.

    Google Scholar 

  38. Meyer R: Subjects rights; Freedom of inquiry and the future of research in the addictions. Am J Psychiatry 134: 899–903, 1977.

    PubMed  CAS  Google Scholar 

  39. Starr C, Whipple C: Risks of risk decisions. Science 208: 1114–1119, 1980.

    Article  PubMed  CAS  Google Scholar 

  40. Weinstein MC: Allocation of subjects in medical experiments. N Engl J Med 291: 1278–1285, 1974.

    Article  PubMed  CAS  Google Scholar 

  41. Mendelson JHG, Miller M, Mello N, Pratt R, Schnitz R: Hospital treatment of alcoholism: A profile of middle income Americans. Alcohol Clin Exp Res 6: 377–383, 1982.

    Article  PubMed  CAS  Google Scholar 

  42. Alfidi RJ: Informed consent: a study of patient reaction. Am Med Assoc 2168: 1325–1329, 1971.

    Article  Google Scholar 

  43. Katz J: Sounding board: The two part consent form. N Engl J Med 290: 964–966, 1974.

    Article  Google Scholar 

  44. Wolfensberger W: Ethical issues in research with human subjects. Science 155: 47–51, 1967.

    Article  PubMed  CAS  Google Scholar 

  45. Schaefferm A: The ethics of the randomized clinical trial. N Engl J Med 307: 719–724, 1982.

    Article  Google Scholar 

  46. Weiss RF, Buchanan W, Altstatt L, Lombardo JP: Altruism is rewarding. Science 171: 1262–1263, 1971.

    Article  PubMed  CAS  Google Scholar 

  47. Marlatt A: Loss of control drinking in alcoholics. J Abnorm Psychol 81: 233, 241, 1973.

    Article  PubMed  CAS  Google Scholar 

  48. Pomerlau O: A critical examination of some current assumptions in the treatment of alcoholism. J Stud Alcohol 37: 849–867, 1976.

    Google Scholar 

  49. Paredes A, Hood WR, Seymour H: Sobrity as a symptom of alcohol intoxication: A clinical commentary on intoxication and drunkenness. Br J Addictions 70: 233–243, 1975.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Brentwood Division, West Los Angeles VA Medical Center, and Department of Psychiatry, School of Medicine, University of California-Los Angeles, Los Angeles, California, 90073, USA

    Alfonso Paredes

Authors
  1. Alfonso Paredes
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. New York University School of Medicine, New York, New York, USA

    Marc Galanter

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer Science+Business Media New York

About this chapter

Cite this chapter

Paredes, A. (1989). Methodological and Ethical Issues in Alcohol Research. In: Galanter, M. (eds) Recent Developments in Alcoholism. Recent Developments in Alcoholism, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1678-5_18

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-1678-5_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1680-8

  • Online ISBN: 978-1-4899-1678-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation