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Expression and Glycosylation of Acetylcholinesterase in Alzheimer’s Disease Brain

From Pathogenesis to Diagnosis

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Abstract

Alzheimer’s disease (AD) is a progressive dementia that commonly occurs in the aged population. It has been estimated that 5–10% of the population over the age of 65 have some cognitive signs of AD (1). Diagnosis of AD remains problematic as clinical examination is only about 80% accurate. To date, no ante mortem biochemical tests have been found which unequivocally indicate a diagnosis of AD.

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© 1998 Springer Science+Business Media New York

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Sáez-Valero, J., Sberna, G., McLean, C., Li, QX., Small, D.H. (1998). Expression and Glycosylation of Acetylcholinesterase in Alzheimer’s Disease Brain. In: Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. (eds) Structure and Function of Cholinesterases and Related Proteins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1540-5_46

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  • DOI: https://doi.org/10.1007/978-1-4899-1540-5_46

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1542-9

  • Online ISBN: 978-1-4899-1540-5

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