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International Handbook of Phobic and Anxiety Disorders in Children and Adolescents pp 207–221Cite as

Obsessive-Compulsive Disorder

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Part of the book series: Issues in Clinical Child Psychology ((ICCP))

Abstract

Obsessive-compulsive disorder (OCD) is characterized by DSM-III-R [American Psychiatric Association (APA), 1987] as recurrent obsessions or compulsions or both that are distressful or interfere in one’s life. Obsessions are defined as persistent thoughts, images, or impulses that are ego-dystonic, intrusive, and, for the most part, senseless. According to DSM-III (APA, 1987, p. 245), “Compulsions are repetitive, purposeful, and intentional behaviors that are performed in response to an obsession, according to certain rules, or in a stereotyped fashion.”

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References

  • Adams, P. L. (1973). Obsessive children. New York: Penguin Books.

    Google Scholar 

  • American Psychiatric Association (1987). Diagnostic and statistical manual of mental disorders, 3rd ed., revised. Washington, DC: Author.

    Google Scholar 

  • Baer, L., & Minichiello, W. E. (1990). Behavior therapy for obsessive-compulsive disorder. In M. Jenike, L. Baer, & W. Minichiello (Eds.), Obsessive compulsive disorders: Theory and management (pp. 203–232). Chicago: Year Book Medical Publishers.

    Google Scholar 

  • Baxter, L. R., Schwartz, J. M., Bergman, K. S., Szuba, M. P., Guze, B. H., Mazziotta, J. C., Alazraki, A., Selin, C. E., Ferng, H.-K., Munford, P., & Phelps, M. E. (1992). Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. Archives of General Psychiatry, 49(9), 681–689.

    Article  PubMed  Google Scholar 

  • Berg, C. Z., Rapoport, J. L., Whitaker, A., Davies, M., Leonard, H., Swedo, S. W., Braiman, S., & Lenane, M. (1989a). Childhood obsessive compulsive disorder: A two-year prospective follow-up of a community sample. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 528–533.

    Article  PubMed  Google Scholar 

  • Berg, C. Z., Rapoport, J. L., & Wolff, R. P. (1989b). Behavioral treatment for obsessive compulsive disorder in childhood. In J. L. Rapoport (Ed.), Childhood obsessive compulsive disorder (pp. 169–185). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Berman, L. (1942). The obsessive-compulsive neurosis in children. Journal of Nervous and Mental Disease, 95, 26–39.

    Article  Google Scholar 

  • Bolton, D., Collins, S., & Steinberg, D. (1983). The treatment of obsessive-compulsive disorder in adolescence: A report of 15 cases. British Journal of Psychiatry, 142, 456–464.

    Article  PubMed  Google Scholar 

  • Borcherding, B. G., Keysor, C., Rapoport, J. L., Elia, J., & Amass, J. (1990). Motor/vocal tics and compulsive behaviors on stimulant drugs: Is there a common vulnerability? Psychiatry Research, 33, 83–94.

    Article  PubMed  Google Scholar 

  • Casas, M., Alvarez, E., Duro, P., & Garcia-Ribera, C. (1986). Antiandrogenic treatment of obsessive-compulsive neurosis. Acta Psychiatrica Scandinavica, 73, 221–222.

    Article  PubMed  Google Scholar 

  • Charney, D. S., Goodman, W. K., Price, L. H., Woods, S. W., Rasmussen, S. A., & Heninger, G. R. (1988). Serotonin function in obsessive compulsive disorder: A comparison of the effects of tryptophan and m-chlorophenylpiperazine in patients and healthy subjects. Archives of General Psychiatry, 45, 177–185.

    Article  PubMed  Google Scholar 

  • Chouinard, G., Goodman, W. K., Griest, J. & Janike, M. (1990). Results of a double-blind placebo controlled trial of a new serotonin uptake inhibitor, sertraline, in the treatment of obsessive-compulsive disorder. Psychopharmacology Bull., 26, 279–284.

    Google Scholar 

  • Cox, C. S., Fedio, P., & Rapoport, J. L. (1989). Neuropsychological testing of obsessive compulsive adolescents. In J. L. Rapoport (Ed.), Obsessive-compulsive disorder in children and adolescents (pp. 73–86). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Crisp, A. H., Lacey, J. H., & Crutchfield, M. (1987). Clomipramine and “drive” in people with anorexia nervosa: An in-patient study. British Journal of Psychiatry, 150, 355–358.

    Article  PubMed  Google Scholar 

  • Cummings, J. L., & Cunningham, K. (1992). Obsessive-compulsive disorder in Huntington’s disease. Biological Psychiatry, 31, 263–270.

    Article  PubMed  Google Scholar 

  • Denckla, M. B. (1989). The neurological examination. In J. L. Rapoport (Ed.), Obsessive-compulsive disorder in children and adolescents (pp. 107–118). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Despert, L. (1955). Differential diagnosis between obsessive-compulsive neurosis and schizophrenia in children. In P. H. Hoch & J. Zubin (Eds.), Psychopathology of childhood (pp. 240–253). New York: Grune & Stratton.

    Google Scholar 

  • Deveaugh-Geiss, J., Moroz, G., Biederman, J., Cantwell, D., Fontaine, R., Greist, J. H., Reichler, R., Katz, R., & Landau, P. (1992). Clomipramine hydrochloride in childhood and adolescent obsessive-compulsive disorder—A multicenter trial. Journal of the American Academy of Child and Adolescent Psychiatry, 31(1), 45–49.

    Article  PubMed  Google Scholar 

  • Elliott, G. R., & Popper, C. W (1991). Editorial: Tricyclic antidepressants: The QT interval and other cardiovascular parameters. Journal of Child and Adolescent Psychopharmacology, 1, 187–191.

    Article  Google Scholar 

  • Esman, A H. (1989). Psychoanalysis and general psychiatry: Obsessive-compulsive disorder as paradigm. Journal of the American Psychoanalytic Association, 37(2), 319–336.

    Article  PubMed  Google Scholar 

  • Flament, M. F., Koby, E., Rapoport, J. L., Berg, C. J., Zahn, T., Cox, C., Denckla, M., & Lenane, M. (1990). Childhood obsessive compulsive disorder: A prospective two-year follow-up study. Journal of Child Psychology and Psychiatry, 31(3), 363–380.

    Article  PubMed  Google Scholar 

  • Flament, M., Rapoport, J. L., Berg, C. J., Sceery, W., Kilts, C., Mellstrom, B., & Linnoila, M. (1985). Clomipramine treatment of childhood obsessive compulsive disorder: A double-blind controlled study. Archives of General Psychiatry, 42, 977–983.

    Article  PubMed  Google Scholar 

  • Flament, M., Whitaker, A., Rapoport, J., Davies, M., Berg, C., Kalikow, K., Sceery, W., & Shaffer, D. (1988). Obsessive compulsive disorder in adolescence: An epidemiological study. Journal of the American Academy of Child and Adolescent Psychiatry, 27(6), 764–771.

    Article  PubMed  Google Scholar 

  • Frankel, M., Cummings, J. L., Robertson, M. M., Trimble, M. R., Hill, M. A., & Benson, D. F. (1986). Obsessions and compulsions in Gilles de la Tourette’s syndrome. Neurology, 36, 378–382.

    Article  PubMed  Google Scholar 

  • Gesell, A., Ames, L. B., & Ilg, F. L. (1974). Infant and child in the culture today. New York: Harper and Row.

    Google Scholar 

  • Goodman, W. K., McDougle, C. J., Price, L. H., Riddle, M. A. Pauls, D. L., & Leckman, J. F. (1990a). Beyond the serotonin hypothesis: A role for dopamine in some forms of obsessive compulsive disorder? Journal of Clinical Psychiatry, 51(Suppl.), 36–43.

    PubMed  Google Scholar 

  • Goodman, W. K., Price, L. H., & Delgado, P. L. (1990b). Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder: Comparison of fluvoxamine and desipramine. Archives of General Psychiatry, 47, 577–585.

    Article  PubMed  Google Scholar 

  • Goodman, W. K., Price, L. H., Rasmussen, S. A., & Delgado, P. L. (1989). Efficacy of fluvoxamine in obsessive-compulsive disorder: A double-blind comparison with placebo. Archives of General Psychiatry, 46, 36–44.

    Article  PubMed  Google Scholar 

  • Gordon, C. T., Rapoport, J. L., Hamburger, S. D., State, R. C., & Mannheim, G. B. (1992). Differential response of seven subjects with autistic disorder to clomipramine and desipramine. American Journal of Psychiatry, 149(3), 363–366.

    PubMed  Google Scholar 

  • Grad, L., Pelcovitz, D., Olson, M., Matthews, M., & Grad, G. (1987). Obsessive-compulsive symptomatology in children with Tourette’s disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 26, 69–73.

    Article  PubMed  Google Scholar 

  • Hamburger, S. D., Swedo, S., Whitaker, A., Davies, M., & Rapoport, J. L. (1989). Growth rate in adolescents with obsessive-compulsive disorder. American Journal of Psychiatry, 46, 652–655.

    Google Scholar 

  • Hollingsworth, C. E., Tanguay, P. E., Grossman, L., & Pabst, P. (1980). Long-term outcome of obsessive-compulsive disorder in childhood. Journal of the American Academy of Child Psychiatry, 19, 134–144.

    Article  PubMed  Google Scholar 

  • Insel, T. R., Mueller, E. A., Alterman, I., Linnoila, M., & Murphy, D. L. (1985). Obsessive-compulsive disorder and serotonin: Is there a connection? Biological Psychiatry, 20, 1174–1188.

    Article  PubMed  Google Scholar 

  • Insel, T. R., Murphy, D. L., Cohen, R. M., Alterman, I., Kilts, C., & Linnoila, M. (1983). Obsessive-compulsive disorder: A double-blind trial of clomipramine and clorgyline. Archives of General Psychiatry, 40, 605–612.

    Article  PubMed  Google Scholar 

  • Janet, P. (1903). Les obsessions et la psychiatrie, Vol. 1. Paris: Felix Alan.

    Google Scholar 

  • Jenike, M. A. (1989). Obsessive-compulsive and related disorders: A hidden epidemic. The New England Journal of Medicine, 321(8), 539–541.

    Article  PubMed  Google Scholar 

  • Jenike, M. A., Baer, L., Summergrad, P., Minichiello, W. E., Holland, A., & Seymour, R. (1990). Sertraline in obsessive-compulsive disorder: A double-blind comparison with placebo. American Journal of Psychiatry, 147, 923–928.

    PubMed  Google Scholar 

  • Jenike, M. A., Buttolph, L., Baer, L., Riccrard, J., & Holland, A. (1989). Open trial of fluoxetine in obsessive-compulsive disorder. American Journal of Psychiatry, 146, 909–911.

    PubMed  Google Scholar 

  • Jenike, M. A., Hynan, S., Baer, L., Holland, A., et al. (1990). A controlled trial of fluoxetine in obsessive-compulsive disorder: Implications for a serotinergic theory. American Journal of Psychiatry, 147, 1209–1215.

    PubMed  Google Scholar 

  • Judd, L. L. (1965). Obsessive compulsive neurosis in children. Archives of General Psychiatry, 12, 136–143.

    Article  PubMed  Google Scholar 

  • Kanner, L. (1962). Child psychiatry, 3rd ed. Springfield, IL: Charles C. Thomas.

    Google Scholar 

  • Kasvikis, Y. G., Tsakiris, F., Marks, I. M. (1986). Women with obsessive compulsive disorder frequently report a past history of anorexia nervosa. International Journal of Eating Disorders, 5, 1069–1075.

    Article  Google Scholar 

  • Keller, B. (1989). Cognitive assessment of obsessive-compulsive children. In J. L. Rapoport (Ed.), Obsessive-compulsive disorder in children and adolescents (pp. 33–39). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Khanna, S., & Srinath, S. (1988). Childhood obsessive compulsive disorder. Psychopathology, 21, 254–258.

    Article  PubMed  Google Scholar 

  • Koizumi, H. M. (1985). Obsessive-compulsive symptoms following stimulants (letter). Biological Psychiatry, 20, 1332–1333.

    Article  PubMed  Google Scholar 

  • Kringlen, E. (1965). Obsessional neurotics: A long-term follow-up. British Journal of Psychiatry, 111, 709–722.

    Article  PubMed  Google Scholar 

  • Kruesi, M. J. P., Rapoport, J. L., Hamburger, S., Hibbs, E., Potter, W. Z., Lenane, M., & Brown, G. L. (1990). CSF monoamine metabolites, aggression and impulsivity in disruptive behavior disorders of children and adolescents. Archives of General Psychiatry, 47, 419–426.

    Article  PubMed  Google Scholar 

  • Lenane, M. (1989). Families and obsessive compulsive disorder. In J. L. Rapoport (Ed.), Obsessive-compulsive disorder in children and adolescents (pp. 237–249). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Lenane, M. C., Swedo, S. E., Leonard, H. L., Pauls, D. L., Sceery, W., & Rapoport, J. L. (1990). Psychiatric disorders in first degree relatives of children and adolescents with obsessive compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 29(3), 407–412.

    Article  PubMed  Google Scholar 

  • Leonard, H. L., Goldberger, E. L., Rapoport, J. L., Cheslow, D. L., & Swedo, S. E. (1990). Childhood rituals: Normal development or obsessive compulsive symptoms. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 17–23.

    Article  PubMed  Google Scholar 

  • Leonard, H. L., Lenane, M. C., Swedo, S. E., Rettew, D. C., Gerson, E. S., & Rapoport, J. L. (1992). Tics and Tourette’s disorder: A 2–7 year follow-up of 54 obsessive compulsive children. American Journal of Psychiatry, 149, 1244–1251.

    PubMed  Google Scholar 

  • Leonard, H. L., Swedo, S. E., Lenane, M. C., Rettew, D. C., Cheslow, D. C., Hamburger, S. D, & Rapoport, J. L. (1991). A double-blind desipramine substitution during long-term clomipramine treatment in children and adolescents with obsessive compulsive disorder. Archives of General Psychiatry, 48, 922–927.

    Article  PubMed  Google Scholar 

  • Leonard, H. L., Swedo, S. E., Lenane, M. C., Rettew, D. C., Hamburger, S. D., Bartko, J. J., & Rapoport, J. L. (1993). A two to seven year follow-up study of 54 obsessive compulsive children and adolescents. Archives of General Psychiatry, 50, 429–439.

    Article  PubMed  Google Scholar 

  • Leonard, H. L., Swedo, S. E., Rapoport, J. L., Koby, E. V., Lenane, M. C., Cheslow, D. L., & Hamburger, S. D. (1989). Treatment of childhood obsessive compulsive disorder with clomipramine and desipramine: A double-blind crossover comparison. Archives of General Psychiatry, 46, 1088–1092.

    Article  PubMed  Google Scholar 

  • Luxenberg, J. S., Swedo, S. E., Flament, M. F., Friedland, R. P., Rapoport, J. L., & Rapoport, S. I. (1988). Neuroanatomic abnormalities in obsessive-compulsive disorder detected with quantitative x-ray computed tomography. American Journal of Psychiatry, 145, 1089–1093.

    PubMed  Google Scholar 

  • Lydiard, R. B., Fossey, M., Krishnan, R., & Goli, V. (1990). CSF monoamine metabolites in obsessive-compulsive disorder. Presented as a poster at the American Psychiatric Association Meeting, May 5, 1990, New York.

    Google Scholar 

  • Marks, I. M. (1981). Review of behavioral psychotherapy. I. Obsessive-compulsive disorders. American Journal of Psychiatry, 138, 584–592.

    PubMed  Google Scholar 

  • Marks, I. M., Hodgson, R., & Rachman, S. (1975). Treatment of chronic obsessive-compulsive neurosis by in-vivo exposure: A two-year follow-up and issues in treatment. British Journal of Psychiatry, 127, 349–364.

    Article  PubMed  Google Scholar 

  • Mavissakalian, M., Turner, S. M., Michelson, L., & Jacob, R. (1985). Tricyclic antidepressants in obsessive-compulsive disorder: Antiobsessional or antidepressant agents? II. American Journal of Psychiatry, 142, 572–576.

    PubMed  Google Scholar 

  • McDougle, C. J., Goodman, W. K., Price, L. H., Delgado, P. L., Krystal, J. H., Chamey, D. S., & Heninger, G. R. (1990). Neuroleptic addition to fluvoxamine-refractory obsessive-compulsive disorder: An open case series. American Journal of Psychiatry, 147, 652–656.

    PubMed  Google Scholar 

  • Montgomery, S. A. (1980). Clomipramine in obsessional neurosis: A placebo-controlled trial. Pharmacologic Medicine, 1, 189–192.

    Google Scholar 

  • Pauls, D. L., Raymond, C. L., Stevenson, J. M., & Leckman, J. F. (1991). A family study of Gilles de la Tourette syndrome. Human Genetics, 48, 154–163.

    Google Scholar 

  • Pauls, D. L., Towbin, K. E., Leckman, J. F., Zahner, G. E., & Cohen, D. J. (1986). Gilles de la Tourette’s syndrome and obsessive-compulsive disorder: Evidence supporting a genetic relationship. Archives of General Psychiatry, 43, 1180–1182.

    Article  PubMed  Google Scholar 

  • Pitman, R. K., Green, R. C., Jenike, M. A., & Mesulam, M. M. (1987). Clinical comparison of Tourette’s disorder and obsessive compulsive disorder. American Journal of Psychiatry, 144, 1166–1171.

    PubMed  Google Scholar 

  • Rachman, S. J., & Hodgson, R. J. (1980). Obsessions and compulsions. Englewood Cliffs, NJ: Prentice-Hall.

    Google Scholar 

  • Rapoport, J. L. (1986). Annotation: Childhood obsessive compulsive disorder. Journal of Child Psychology and Psychiatry, 27, 289–296.

    Article  PubMed  Google Scholar 

  • Rettew, D. C., Swedo, S. E., Leonard H. L., Lenane, M. C., & Rapoport, J. L. (1992). Obsessions and compulsions across time in 79 children and adolescents with obsessive compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 31(6), 1050–1056.

    Article  PubMed  Google Scholar 

  • Riddle, M. A., Hardin, M. T., King, R., Scahill, L., & Woolston, J. L. (1992a). Fluoxetine treatment of children and adolescents with Tourette’s and obsessive compulsive disorders: Preliminary clinical experience. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 45–48.

    Article  Google Scholar 

  • Riddle, M. A., King, R. A., & Hardin, M. T. (1991). Behavioral side effects of fluoxetine in children and adolescents. Journal of Child and Adolescent Psychopharmacology, 1, 193–198.

    Article  Google Scholar 

  • Riddle, M. A., Scahill, L., King, R. A., Hardin, M. T., Anderson, G. M., Ort, S. I., Smith, J. C., Leckman, J. F., & Cohen, D. J. (1994). Double-blind, crossover trial of fluoxetine and placebo in children and adolescents with obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent, 31(6), 1062–1069.

    Article  Google Scholar 

  • Riddle, M. A., Scahill, L., King, R., Hardin, M. T., Towbin, K. E., Ort, S. I., Leckman, J. F., & Cohen, D. J. (1992b). Obsessive compulsive disorder in children and adolescents: Phenomenology and family history. Journal of the American Academy of Child and Adolescent Psychiatry, 29(5), 766–772.

    Article  Google Scholar 

  • Rutter, M., Tizard, J., & Whitmore, K. (1970). Education, health and behavior. London: Longmans.

    Google Scholar 

  • Swedo, S. E. (1989). Rituals and releasers: An ethological model of OCD. In J. L. Rapoport (Ed.), Obsessive-compulsive disorder in children and adolescents (pp. 269–288). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Swedo, S. E., & Rapoport, J. L. (1990). Neurochemical and neuroendocrine considerations of obsessive compulsive disorders in childhood. In S. I. Deutsch, A. Weizman, & R. Weizman (Eds.), Application of basic neuroscience to child psychiatry (pp. 275–284). New York: Plenum Press.

    Chapter  Google Scholar 

  • Swedo, S. E., Leonard, H. L., Kruesi, M. J. P., Rettew, D. C., Listwak, S. J., Berretini, W., Stipetic, M., Hamburger, S., Gold, P. W., Potter, W. Z., & Rapoport, J. L. (1992). Cerebrospinal fluid neurochemistry in children and adolescents with obsessive compulsive disorder. Archives of General Psychiatry, 49, 29–36.

    Article  PubMed  Google Scholar 

  • Swedo, S. E., Leonard, H. L., Rapoport, J. L., Lenane, M. C., Goldberger, E. L., & Cheslow, D. L. (1989a). A double-blind comparison of clomipramine and desipramine in the treatment of trichotillomania. New England Journal of Medicine, 321, 497–501.

    Article  PubMed  Google Scholar 

  • Swedo, S. E., Leonard, H. L., Schapiro, M. B., Casey, B. J., Mannheim, G. B., Lenane, M. C., & Rettew, D. C. (1993). Sydenham’s chorea: Physical and psychological symptoms of St. Vitus’ dance. Pediatrics, 91(4), 706–713.

    PubMed  Google Scholar 

  • Swedo, S. E., Rapoport, J. L., Cheslow, D. L., Leonard, H. L., Ayoub, E. M., Hosier, D. M., & Wald, E. R. (1989b). High prevalence of obsessive-compulsive symptoms in patients with Sydenham’s chorea. American Journal of Psychiatry, 146(2), 246–249.

    PubMed  Google Scholar 

  • Swedo, S. E., Rapoport, J. L., Leonard, H., Lenane, M., & Cheslow, D. (1989c). Obsessive-compulsive disorder in children and adolescents. Archives of General Psychiatry, 46, 335–344.

    Article  PubMed  Google Scholar 

  • Swedo, S. E., Schapiro, M. B., Grady, C. L., Cheslow, D. L., Leonard, H. L., Kumar, A., Friedland, R., Rapoport, S. I., & Rapoport, J. L. (1989d). Cerebral glucose metabolism in childhood-onset obsessive compulsive disorder. Archives of General Psychiatry, 46, 518–523.

    Article  PubMed  Google Scholar 

  • Thomsen, P. H., & Mikkelsen, H. U. (1991). Children and adolescents with obsessive-compulsive disorder: The demographic and diagnostic characteristics of 61 Danish patients. Acta Psychiatrica Scandinavica, 83, 262–266.

    Article  PubMed  Google Scholar 

  • Thoren, P., Asberg, M., Cronholm, B., Jornestedt, L., & Traskman, L. (1980). Clomipramine treatment of obsessive-compulsive disorder. I. A controlled clinical trial. Archives of General Psychiatry, 37, 1281–1285.

    Article  PubMed  Google Scholar 

  • van Amerongen, S. T. (1980). Latency and prepubertal children. In J. Noshpitz (Ed.), Basic Handbook of Child Psychiatry, Vol. III (pp. 495–504). New York: Basic Books.

    Google Scholar 

  • Volavka, J., Neziroglu, F., & Yaryura-Tobias, J. A. (1985). Clomipramine and imipramine in obsessive-compulsive disorder. Psychiatry Research, 14, 83–91.

    Article  Google Scholar 

  • von Economo, C. (1931). Encephalitis lethargical Its sequelae and treatment. London: Oxford University Press.

    Google Scholar 

  • Warren, W. (1960). A study of adolescent psychiatric in-patients and the outcome six or more years later. Journal of Child Psychology and Psychiatry, 6, 141–160.

    Article  Google Scholar 

  • World Health Organization (1992). International classification of mental and behavioral disorders, clinical descriptions and diagnostic guidelines, 10th ed. (ICD-10). Geneva: Author.

    Google Scholar 

  • Zohar, J., Mueller, E. A., Insel, T. R., Zohar-Kadouch, R., & Murphy, D. (1987). Serotonergic responsivity in obsessive-compulsive disorder: Comparison of patients and healthy controls. Archives of General Psychiatry, 44, 946–951.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Child Psychiatry Branch, National Institute of Mental Health, Rockville, Maryland, 20892, USA

    Henrietta L. Leonard, Susan E. Swedo, Albert J. Allen & Judith L. Rapoport

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  1. Henrietta L. Leonard
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  2. Susan E. Swedo
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  3. Albert J. Allen
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  4. Judith L. Rapoport
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Editors and Affiliations

  1. Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, 24061-0436, USA

    Thomas H. Ollendick

  2. Department of Education, Monash University, Clayton, 3168, Victoria, Australia

    Neville J. King

  3. Institute of Psychiatry, University of London, London, SE5 8AF, UK

    William Yule

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Leonard, H.L., Swedo, S.E., Allen, A.J., Rapoport, J.L. (1994). Obsessive-Compulsive Disorder. In: Ollendick, T.H., King, N.J., Yule, W. (eds) International Handbook of Phobic and Anxiety Disorders in Children and Adolescents. Issues in Clinical Child Psychology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1498-9_11

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