Abstract
Unlike the rat, the cat is dependent upon a dietary source of taurine. Cats maintained on taurine-deficient diets show profound and rapid falls in plasma taurine concentrations, followed by slower falls in tissue concentrations. Taurine deficiency in cats is associated with a large number of problems, including retinal degeneration and blindness (1), dilated cardiomyopathy (9), and reproductive (11) and developmental disorders (10,12).
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References
Hayes, K.C., Carey, R.E., and Schmidt, S.Y. 1975, Retinal degeneration associated with taurine deficiency in the cat, Science, 188:949–951.
Huxtable, R.J. 1987, From heart to hypothesis: a mechanism for the calcium modulatory actions of taurine, in: “The Biology of Taurine: Methods and Mechanisms”, Huxtable, R.J., Franconi, F. and Giotti, A., eds., Plenum Press, New York, pp. 371–388.
Huxtable, R.J. 1990, The interaction between taurine, calcium and phospholipids: Further investigations of a trinitarian hypothesis, in: “Taurine: Functional Neurochemistry, Physiology, and Cardiology”, Pasantes-Morales, H., Martin, D.L., Shain, W. and del Río, R.M., eds., Wiley-Liss, New York, pp. 185–196.
Huxtable, R.J., Crosswell, S., and Parker, D. 1989, Phospholipid composition and taurine content of synaptosomes in developing rat brain, Neurochem.International, 15:233–238.
Huxtable, R.J., Murphy, J., and Lleu, P.-L. 1994, Developmental effects of taurine depletion on synaptosomal phospholipids in the rat, in: “Taurine in Health and Disease”, Huxtable, R.J. and Michalk, D., eds., Plenum Press, New York, this volume.
Huxtable, R.J. and Sebring, L.A. 1986, Towards a unifying theory for the action of taurine, Trends Pharmacol.Sci., 7:481–485.
Huxtable, R.J. and Sebring, L.A. 1989, Taurine and the heart: the phospholipid connection, in: “Taurine and the Heart”, Iwata, H., Lombardini, J.B. and Segawa, T., eds., Kluwer Academic Press, Boston, pp. 31–42.
Lleu, P.-L. and Huxtable, R.J. 1992, Phospholipid methylation and taurine content of synaptosomes from cerebral cortex of developing rat, Neurochem.International, 21:109–118.
Pion, P.D., Kittleson, M.D., Rogers, Q.R., and Morris, J.G. 1987, Myocardial failure in cats associated with low plasma taurine: a reversible cardiomyopathy, Science, 237:764–768.
Sturman, J.A., Gargano, A.D., Messing, J.M., and Imaki, H. 1986, Feline maternal taurine deficiency: effect on mother and offspring, J.Nutr., 116:655–667.
Sturman, J.A. and Messing, J.M. 1991, Dietary taurine content and feline reproduction and outcome, J.Nutr., 121:1195–1203.
Sturman, J.A., Moretz, R.C., French, J.H., and Wisniewski, H.M. 1985, Postnatal taurine deficiency in the kitten results in a persistence of the cerebellar external granule cell layer: correction by taurine feeding, J.Neurosci.Res., 13:521–528.
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© 1994 Springer Science+Business Media New York
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Lleu, PL., Bowers, R.J., Gargano, A., Sturman, J., Huxtable, R.J. (1994). Taurine Depletion and Synaptosomal Phospholipid Content in Cat Brain. In: Huxtable, R.J., Michalk, D. (eds) Taurine in Health and Disease. Advances in Experimental Medicine and Biology, vol 359. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1471-2_36
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DOI: https://doi.org/10.1007/978-1-4899-1471-2_36
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