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Mechanisms Underlying Physiological and Pharmacological Actions of Taurine on Myocardial Calcium Transport

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Taurine in Health and Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 359))

Abstract

One of the major functions of taurine in the heart is the modulation of calcium transport (21). Depending on the status of the myocardium, taurine is capable of either increasing or decreasing intracellular calcium levels (21). This complicated biphasic pattern has been difficult to resolve mechanistically. The only rational explanation for this phenomenon assumes that taurine exerts multiple effects on calcium transport, some which promote myocyte calcium accumulation while others enhance cellular calcium loss.

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© 1994 Springer Science+Business Media New York

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Schaffer, S.W., Ballard, C., Azuma, J. (1994). Mechanisms Underlying Physiological and Pharmacological Actions of Taurine on Myocardial Calcium Transport. In: Huxtable, R.J., Michalk, D. (eds) Taurine in Health and Disease. Advances in Experimental Medicine and Biology, vol 359. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1471-2_18

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  • DOI: https://doi.org/10.1007/978-1-4899-1471-2_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1473-6

  • Online ISBN: 978-1-4899-1471-2

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