Abstract
The liver and brain are organs rich in taurine (14,17). Taurine is present at high concentrations in liver and brain of developing mammals, and, may be important in normal fetal and neonatal development (11,29). In the brain, a role of taurine as an inhibitory neurotransmitter or neuromodulator has been proposed (13,20). A number of immunohistochemical studies have clarified the localization of taurine (3,31) or its synthesizing enzyme, cysteine sulfinic acid decarboxylase (4). However, the localization of taurine in the liver has not been well settled. In our previous immunohistochemical studies using antiserum to taurine, we have found that the antiserum recognizes not only taurine in the brain but also bile acids conjugated with taurine in the liver (15,7,30).
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Ding, W.G., Tooyama, I., Kimura, H., Kuriyama, K. (1994). Immunohistochemical Localization of Taurine-Conjugated Bile Acids in the Liver of Mouse, Rat, Monkey and Human. In: Huxtable, R.J., Michalk, D. (eds) Taurine in Health and Disease. Advances in Experimental Medicine and Biology, vol 359. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1471-2_10
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DOI: https://doi.org/10.1007/978-1-4899-1471-2_10
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