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Neurochemical and Behavioral Sequelae of Exposure to Dioxins and PCBs

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Dioxins and Health

Abstract

In a previous review of the literature related to the toxicity of polychlorinated biphenyls (PCBs), one of the present authors1 reviewed the experimental evidence demonstrating that one of the major classes of PCBs—the ortho-substituted congeners—were capable of altering neurological function in a wide variety of experimental preparations. In this chapter we broaden the review to include a discussion of the behavioral effects of exposure as well as contributions that coplanar PCBs, dioxins (PCDDs), and di-benzofurans (PCDFs) make to the overall neurotoxic risk to humans from exposure to complex environmental mixtures.

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  1. Richard F. Seegal

    Present address: School of Public Health, University at Albany, State University of New York, Albany, New York, 12203, USA

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  1. New York State Department of Health, Wadsworth Center for Laboratories and Research, Albany, New York, 12201, USA

    Richard F. Seegal

  2. School of Public Health, University at Albany, State University of New York, Albany, New York, 12203, USA

    Susan L. Schantz

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  1. Department of Preventive Medicine, University of New York Health Science Center-Syracuse, Binghamton, New York, 13903, USA

    Arnold Schecter

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Seegal, R.F., Schantz, S.L. (1994). Neurochemical and Behavioral Sequelae of Exposure to Dioxins and PCBs. In: Schecter, A. (eds) Dioxins and Health. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1462-0_13

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