Abstract
The corpus callosum is the principal pathway for the communication of sensory and cognitive information between cortical areas of the two cerebral hemispheres (Sperry 1982; Gazzaniga 1985; Sperry 1974) and has been the subject of considerable clinical interest due to its role as the primary substrate for the interhemispheric spread of discharges in generalized epileptic seizures (Reeves and O’Leary 1985; Wilson et al. 1975). Studies of callosal connections within sensory and motor regions of the cerebral cortex over the past 30 years have provided important insight into the functional, organizational and developmental features of these pathways. In contrast, the study of callosal connections for association regions of the cerebral mantle has not kept pace. In this chapter, I will present data from ongoing studies of corticocortical connectivity in which we have focused on the organization and development of interhemispheric connections between areas of the monkey prefrontal association cortex. I will first describe general features of the topographic, laminar, and columnar organization of these connections in the mature monkey and will conclude with results of our studies examining the prenatal development and maturation of these connections.
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Schwartz, M.L. (1995). Organization and Development of Interhemispheric Connections of the Prefrontal Cortex in Rhesus Monkey. In: Reeves, A.G., Roberts, D.W. (eds) Epilepsy and the Corpus Callosum 2. Advances in Behavioral Biology, vol 45. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1427-9_4
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