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Some Historical Aspects of Callosotomy for Epilepsy

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Epilepsy and the Corpus Callosum 2

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 45))

Abstract

The large size, central location and widespread connections of the corpus callosum stimulated, for centuries, investigations which were motivated as much by scientific curiosity as by therapeutic considerations. Callosal physiology has more recently been important to surgeons concerned primarily with other structures, including those neighboring the third ventricle, which can be approached through the corpus callosum. But the principal medical interest has been in the role of the corpus callosum in the generalization of seizures. At the end of the 19th century and on two other, separate occasions in the 20th century, callosotomy was promoted as a treatment for seizure disorders. Before 1900, less obviously around 1940, and most clearly in the 1960’s, these therapeutic proposals were stimulated by animal experimentation. One theme of this chapter is the reciprocal interaction of surgical therapy and laboratory experimentation: in particular, the most recent therapeutic use of callosotomy has been accompanied by widespread physiologic and psychologic interest in this conspicuous brain structure.

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Bogen, J.E. (1995). Some Historical Aspects of Callosotomy for Epilepsy. In: Reeves, A.G., Roberts, D.W. (eds) Epilepsy and the Corpus Callosum 2. Advances in Behavioral Biology, vol 45. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1427-9_11

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  • DOI: https://doi.org/10.1007/978-1-4899-1427-9_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1429-3

  • Online ISBN: 978-1-4899-1427-9

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