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Regulation of Gene Transcription of Angiotensin II Receptor Subtypes in the Heart

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Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 396))

Abstract

The process of left ventricular remodeling after acute myocardial infarction involves alterations in the topography of both infarcted and noninfarcted ventricular regions (1). In the infarcted area, infarct expansion with regional dilation and thinning of the infarct zone occur within 1 day after myocardial infarction (2). The myocardium remote from the area of infarction is subjected to increased diastolic wall stress (2, 3), resulting in myocyte slippage (3) as well as myocyte hypertrophy (4). The myocardial hypertrophy exhibits characteristics of combined pressure and volume overload (4, 5).

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Authors and Affiliations

  1. Second Department of Internal Medicine, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

    Hiroaki Matsubara, Yutaka Nio, Satoshi Murasawa, Kazuhisa Kijima, Katsuya Maruyama, Yasukiyo Mori & Mitsuo Inada

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  1. Hiroaki Matsubara
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  2. Yutaka Nio
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  3. Satoshi Murasawa
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  4. Kazuhisa Kijima
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  5. Katsuya Maruyama
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  6. Yasukiyo Mori
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Editors and Affiliations

  1. University of Florida, Gainesville, Florida, USA

    Mohan K. Raizada , M. Ian Phillips  & Colin Sumners ,  & 

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© 1996 Springer Science+Business Media New York

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Matsubara, H. et al. (1996). Regulation of Gene Transcription of Angiotensin II Receptor Subtypes in the Heart. In: Raizada, M.K., Phillips, M.I., Sumners, C. (eds) Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors. Advances in Experimental Medicine and Biology, vol 396. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1376-0_3

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  • DOI: https://doi.org/10.1007/978-1-4899-1376-0_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1378-4

  • Online ISBN: 978-1-4899-1376-0

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