Abstract
Allium plants have been grown for many centuries for their characteristic, pungent flavor and medicinal properties. In ancient China, Egypt, and India, Allium plants (especially onion and garlic) are highly prized as foodstuffs. With regard to the chemical constituents in Allium plants, early investigations have been focused on the volatile compounds (sulfur-containing compounds) and their products, their (involatile) precursors, and the biochemical basis of flavor production.1 Since the tremendous improvements over the last two decades in techniques for the isolation, separation, and analysis of complex structures have been achieved, a variety of steroidal saponins have been isolated from Allium spp. such as A. sativum,2 A. ampeloprasum,3 A. vineale,4 and A. cepa 5. The important biological activities of the saponins are of increasing interest as recently illustrated by their potential value as antifungal agents 2,3 and anti-thrombotic agents.6
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
M.H. Brodnitz, C.L. Pollock, and P.P. Vallon, Flavor components of onion oil, J. Agric. Food Chem. 17: 760 (1969);
M. H. Brodnitz and J. V. Pascale, Thiopropanal S-oxide, a lachrymatory factor in onion, J. Agric. Food Chem. 19: 269 (1971);
M. Boelens, P. J. deValois, H. J. Wobben, and A. Van der Gan, Volatile flavor compouds from onion, J. Agric. Food Chem. 19: 984 (1971).
L. Schreyen, P. Dirinck, F.Van Wassenhove, and N. Schamp, Volatile flavor components of leek, J Agric. Food Chem. 24: 336 (1976).
a) H. Mutsuura, T. Ushiroguchi, Y. Itakura, N. Hayashi, and T. Fuwa, A furostanol glycoside from garlic, bulbs of Allium sativum L., Chem. Pharm. Bull., 36: 3659 (1988);
H. Mutsuura, T. Ushiroguchi, Y. Itakura, and T. Fuwa, Further studies on steroidal glycosides from bulbs, roots, and leaves of Allium sativum L., Chem. Pharm. Bull., 37: 2741 (1989).
T. Morita, T. Ushiroguchi, N. Hayashi, H. Matsuura, Y. Itakura, and T. Fuwa, Steroidal saponins from elephant garlic, bulbs of Allium ampeloprasum L., Chem. Pharm. Bull. 36: 3480 (1988).
S. X. Chen and J. K. Snyder, Diosgenin-bearing, molluscicidal saponins from Allium vineale: an NMR approach for the structural assignment of oligosaccharide units, J. Org. Chem. 54: 3679 (1989).
P. K. Kintya and L. P. Degtyareva, Steroid glycosides of garden onion seeds. Structure of ceposide D, Khim. Prir. Soedin. (1): 139 (1988).
A. Niwa, O. Takeda, M. Ishimaru, Y. Nakamoto, K. Yamasaki, H. Konda, H. Nishio, T. Segawa, K. Fujimura, and A. Kuramoto, Screening test for platelet aggregation inhibitor in natural products. The active principle of Anmarrhenae rhizoma, Yakugaku Zasshi 108: 555 (1988);
J. X. Dong and G.Y. Han, Studies on the active constituents of Anemarrhena asphodeloides Bunge, Acta Pharm. Sinica, 27: 26 (1992).
Jiang Su New Medical College (ed.). Encyclopedia of Chinese Materia Medica, Shanghai Science and Technology Publisher, Shanghai 2642 (1977).
Institute of Botany, Chinese Academy of Sciences (ed.). Zhongguo Zhiwuzhi, Science Press, Beijing 14:260 (1980).
Beijing Institute of Materia Medica (ed.). Zhongyaozhi (II), People’s Health Publishing House, 2nd ed., Beijing 564 (1982).
J. P. Peng, Y. Wu, X.S. Yao, T. Okuyama, and T. Narui, Two new steroidal saponins from Allium macrostemon, Acta Pharm. Sinica 27: 918 (1992).
J. P. Peng, X. Wang, and X. S.Yao, Studies on two new furostanol glycosides from Allium macrostemon Bunge, Acta Pharm. Sinica 28: 526 (1993).
J. P. Peng, X. S. Yao, Y. Okada, and T. Okuyama, Structures of macrostemonoside J, K and L from Allium macrostemon Bunge, Acta Pharm. Sinica 29: 526 (1994).
P. K. Agrawal, D. C. Jain, R. K. Guita, and R. S. Thakur, Carbon-13 NMR spectroscopy of steroidal sapogenins and steroidal saponins, Phytochemistry 24: 2479 (1985).
R. Saiji, K. Muradami, T. Nohara, T. Tomimatsu, A. Sato, and K. Matsuka, Studies on the constituents of Solanum plants. H. On the constituents of immature berries of Solanum nigrum L., Yakugaku Zasshi, 102: 300 (1982).
J. P. Peng, X. S. Yao, H. Kobayashi, and C. Y. Ma, Novel furostanol glycosides from Allium macrostemon. Planta Med., 61: 58 (1995).
H. Mutsuura, T. Ushiroguchi, Y. Itakura, and T. Fuwa, A furostanol glycoside from Allium chinense G. Don, Chem. Pharm. Bull. 37: 1390 (1989).
X. C. Li, D. Z. Wang, and C. R. Yang, Steroidal saponins from Chlorophytum maloyense, Phytochemistry 29: 3893 (1990).
T. Okuyama, S. Shibata, M. Hoson, T. Kawada, H. Osada, and T.Noguchi, Effect of oriental plant drugs on platelet aggregation; III. Effect of Chinese drug “Xiebai” on human platelet aggregation, Planta Med. 52: 171 (1986);
T. Okuyama, K. Fujita, S. Shibata, M. Hoson, T. Kawada, M. Masaki, and N. Yamate, Effects of Chinese drugs “Xiebai” and “Dasuan” on human platelet aggregation, Planta Med. 55: 242 (1989).
Y. Goda, M. Shibuta, and U. Sankawa, Inhibitors of the arachidonate cascade from Allium chinense and their effect on in vitro platelet aggregation, Chem. Pharm. Bull. 35: 2668 (1987).
J. P. Peng, X. S. Yao, Y. Tezuka, and T. Kikuchi, Two furostanol glycosides from Allium chinense bulbs, Phytochemistry (accepted, 1996 )
J. Blackwood and S. Fulder, Garlic: Nature’s Original Remedy, Javelin Books, London 1986.
G. Vernin, J. Metzger, D.Fraisse, and C. Scharff, GC-MS computer analysis of volatile sulfur compounds in garlic essential oils. Application of the mass fragmentometry SIM technique, Planta Med. 52: 96 (1986).
E. Block, S. Ahmad, M. K. Jain, R. W. Crecely, R. Apitz-Castro, and M. R. Cruz, (E, Z)-ajoene: a potent antithrombotic agent from garlic, J. Am. Chem. Soc. 106: 8295 (1984).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Springer Science+Business Media New York
About this chapter
Cite this chapter
Peng, Jp., Yao, Xs. (1996). 19 New Steroidal Saponins from Allium Plants: Isolation, Structural Elucidation and Effect on Blood Coagulability. In: Waller, G.R., Yamasaki, K. (eds) Saponins Used in Traditional and Modern Medicine. Advances in Experimental Medicine and Biology, vol 404. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1367-8_42
Download citation
DOI: https://doi.org/10.1007/978-1-4899-1367-8_42
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-1369-2
Online ISBN: 978-1-4899-1367-8
eBook Packages: Springer Book Archive