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New Cardioactive Steroid Saponins and Other Glycosides from Mexican Tribulus cistoides

  • Hans Achenbach
  • Harald Hübner
  • Melchior Reiter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 404)

Abstract

The genus Tribulus of the Zygophyllaceae comprises about 20 species which grow as shrubs or herbs in subtropical areas around the world1,2. Among the Tribulus species, only T. terrestris has been investigated phytochemically3–6. This plant is known in South Africa and the USA to be toxic for sheep and causes major economic damage2,7. On the other hand, T. terrestris is used in Ayurvedic medicine against various diseases8 and its extract constitutes the active component of a medicine traded in Bulgaria9,10.

Keywords

Aerial Part Root Extract Sugar Moiety MeOH Extract Positive Inotropic Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    H. Melchior. A. Engler’s Syllabus der Pflanzenfamilien, edn. 12, Vol. 2. Gebrüder Bornträger, Berlin-Nikolassee (1964); p. 251.Google Scholar
  2. 2.
    R. Hegnauer. Chemotaxonomie der Pflanzen, Vol. 6. Birkhäuser, Basel (1973); p. 707.Google Scholar
  3. 3.
    S.B. Mahato, N.P. Sahu, A.N. Ganguly, K. Miyahara, and T. Kawasaki. Steroidal glycosides of Tribulus terrestris Linn. J. Chem. Soc. Perkin Trans. I, 2405 (1981).Google Scholar
  4. 4.
    M.P. Tomowa, D. Panowa, and N.S. Wulfson. Steroid-saponine und Steroidsapogenine, IV. Mitteilung, Saponine aus Tribulus terrestris. Planta Med. 25, 231 (1974).PubMedCrossRefGoogle Scholar
  5. 5.
    M.P. Tomowa and R. Gjulemetowa. Steroidsaponine und Steroidsapogenine, VI. Furostanolbisglykosid aus Tribulus terrestris L. Planta Med. 34, 188 (1978).Google Scholar
  6. 6.
    E.D. Perepelitsa and P.K. Kintya. Chemical study of steroid glycosides of Tribulus terrestris, IV. Steroid saponins. Khim. Prir. Soedin. 11, 260 (1975);Google Scholar
  7. E.D. Perepelitsa and P.K. Kintya. Through Chem. Abstr. 83, 128650t (1975).Google Scholar
  8. 7.
    J.M. Watt and M.G. Breyer-Brandwijk. The Medicinal and Poisonous Plants-of Southern and Eastern Africa, edn. 2. E. & S. Livingstone, Edinburgh (1962); p. 1067.Google Scholar
  9. 8.
    B. Chakraborty and N.C. Neogi. Pharmacological properties of Tribulus terrestris Linn. Indian J. Pharm. Sci., 50 (1978).Google Scholar
  10. 9.
    M. Tomova, R. Gjulemetova, S. Zarkova, S. Peeva, T. Pangarova, and M. Simova. Steroidal saponins from Tribulus terrestris L. with a stimulating action on the sexual functions. In: International Conference on Chemistry and Biotechnology of Biologically Active Natural Products (Atanasova, B., Ed.) Vol. 3. Bulg. Acad. Sci., Sofia (1981); p. 298.Google Scholar
  11. 10.
    M. Tomova. Tribestan. Farmatsiya (Sofia) 37, 40 (1987);Google Scholar
  12. M. Tomova. Through Chem. Abstr. 108, 161409d (1988).Google Scholar
  13. 11.
    J.L. Diaz. Indice y Sinonimia de las Plantas Medicinales de México. Inst. Méx. Estud. Plant. Med., México (1976); p. 325.Google Scholar
  14. 12.
    E.S. Ayensu. Medicinal Plants of the West Indies. Reference Publications, Algonac (1981); p. 196.Google Scholar
  15. 13.
    M. Reiter, personal communication (1987).Google Scholar
  16. 14.
    H. Achenbach and H. Hübner. Cardioactive steroid saponins and other constituents from the aerial parts of Tribulus cistoides. Phytochemistry 35, 1527 (1994).PubMedCrossRefGoogle Scholar
  17. 15.
    A. De Bruyn, M. Anteunis, R. van Rijsbergen, M. Claeyssens, and P. Kovâc. 1H NMR study of methyl 0-acetyl-a-and -ß-xylopyranosides. Conformational studies and non additivity of 1H-shift increments. J. Carbohydr. Chem. 1, 301 (1983).CrossRefGoogle Scholar
  18. 16.
    H. Achenbach, H. Hübner, and M. Reiter. Cholestane-and pregnane-type glycosides from the roots of Tribulus cistoides. Phytochemistry 41, 907 (1996).PubMedCrossRefGoogle Scholar
  19. 17.
    M. Reiter. Die Wertbestimmung inotrop wirkender Arzneimittel am isolierten Papillarmuskel. Arzneim. Forsch. 17, 1249 (1967).Google Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Hans Achenbach
    • 1
  • Harald Hübner
    • 1
  • Melchior Reiter
    • 1
  1. 1.Institute of Pharmacy and Food Chemistry Department of Pharmaceutical ChemistryUniversity of ErlangenErlangenGermany

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