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Effect of Some Saponins on Glucose Transport System

  • Kazuo Yamasaki
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 404)

Abstract

Glucose is the most important nutrient for many types of cells. Indeed, some tissues, such as our own brain, are almost entirely dependent upon glucose as an energy source. Since glucose is a hydrophilic molecule, its uptake into cells across the hydrophobic core of the plasma needs some help. In mammals, where complex homeostatic mechanisms keep the blood glucose level roughly constant, most cells contain a passive facilitated diffusion system for sugar uptake, called the glucose transporter. Previously, this name was based on its function, however, at present, its substantial structure has been established. It is a protein constituted of about five hundred amino acid residues and localised on the surface of the cell membranes in many tissues and organs. In other words, most cells contain passive facilitated diffusion systems for sugar uptake. There are active. sodium-linked sugar transporters in certain locations, such as the kidney and small intestine, where transepithelial transport against a concentration gradient is required.1

Keywords

Panax Ginseng Sheep Erythrocyte Ehrlich Ascites Tumor Cell Ginseng Extract Triterpenoid Saponin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Kazuo Yamasaki
    • 1
  1. 1.Hiroshima UniversityMinami-ku Hiroshima 734Japan

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