Abstract
Saponins constitute bioactive substances of vegetal origin, having a wide variety of biological activities. Special mention should be made of their antimicrobial and fungicidal activity1,2. The general structure of such compounds may be viewed as consisting of two distinct regions, namely the polysaccharidic chain and the genin part, having a rigid steroid skeleton of the molecule which together represent the biologically active properties of such compounds.
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References
A.S. Dimoglo, I.N. Choban, and I.R. Bersuker, Structure-activity corelation for antioxidant and antifungal properties of steroid glycosides, J. Bioorg. Chem. 11: 408 (1985).
P. Ehrlich, Collected Studies on Immunology, 1906, 2:42–48 cited by R. Arshady, J. Bioact. Comp. Polym. 5: 315 (1990).
R.M. Ottembrite, in: The Import of Chemistry on Biotechnology, M. Phillips, S.P. Shoemaker, R.D. Middlekauff and R.M. Ottembrite, Eds., ACS Symposium Series, 362:122 (1988).
R.M. Ottembrite, in Polymeric Drugs and Drugs Delivery Systems, R.L. Dunn and R.M. Ottembrite, Eds., ACS Symposium Series, 469:3 (1991).
R.G. Douglas, Antiviral drugs, Med. Clin. Amer. 67: 1163 (1983).
P.K. Kintia, G.V. Lazurievsky, N.N. Balashova, I.I. Suruahin, and V.A. Lyakh, Structure and Biological Activity of Steroid Glycosides of the Spirostan and Furostan Series, Shtiintsa, Kishinev (1987).
V.A. Bobeyko, P.K. Kintia, and I.V. Dranka, Thermal decomposition of furostanol glycoside-tomatoside, J. Thermal Anal. 36: 1307 (1990).
T. Kawasaki, I. Nishioka, T. Komori, T. Yamauchi, and K. Miyahara, Digitalis saponins, Tetrahedron 21: 299 (1965).
R. Tschesche, A.M. Javellana, and G. Wulff, Purpureagitosid, ein bisdesmosidisches 22-Hydroxyfurostanol-Glycosid aus den Glattem von Digitalis purpurea L., Chem. Ber. 107: 2828 (1974).
C.V. Uglea, I.N. Albu, A. Vatajanu, M. Croitoru, D. lurea, M. Isac, and R.M. Ottembrite, Polyanionic Polymers. I. Synthesis, Characterization, and Potential Medical Applications of Benzocaine modified carboxymethylcellulose, J. Bioact. Compat. Polym. 9: 448 (1994).
E. Maesawa and T. Kosijama, Properties of 2,3-dicaboxycellulose metallic salts, Cell Chem. Technol. 18: 31 (1984).
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© 1996 Springer Science+Business Media New York
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Iurea, D., Uglea, C.V., Kintia, P.K. (1996). Modified Steroidal Glycosides with Potential Biological Activity. In: Waller, G.R., Yamasaki, K. (eds) Saponins Used in Traditional and Modern Medicine. Advances in Experimental Medicine and Biology, vol 404. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1367-8_11
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DOI: https://doi.org/10.1007/978-1-4899-1367-8_11
Publisher Name: Springer, Boston, MA
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