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Prostaglandins and Related Compounds Lipid Messengers with Many Actions

  • Elizabeth A. Meade
  • David A. Jones
  • Guy A. Zimmerman
  • Thomas M. McIntyre
  • Stephen M. Prescott
Part of the Handbook of Lipid Research book series (HLRE, volume 8)

Abstract

Prostaglandins are oxidized derivatives of arachidonic acid that are produced by many tissues in response to specific stimuli. These biologically active lipids are not stored within cells but rather synthesized and released on stimulation to function in an autocrine or paracrine fashion. Prostaglandins serve diverse physiological and pathophysiological functions, affecting all major systems of the body, and mediating such physiological processes as vascular homeostasis, renal water absorption, ovulation, and parturition. In addition, prostaglandins have been implicated as pathological mediators in thrombosis, asthma, and inflammatory disorders such as arthritis.

Keywords

Arachidonic Acid Arachidonic Acid Release Prostaglandin Biosynthesis Prostaglandin Synthetase Prostaglandin Endoperoxide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Elizabeth A. Meade
    • 1
  • David A. Jones
    • 2
  • Guy A. Zimmerman
    • 3
  • Thomas M. McIntyre
    • 4
  • Stephen M. Prescott
    • 5
  1. 1.The Eccles Program in Human Molecular Biology and Genetics and the Nora Eccles Harrison Cardiovascular Research and Training InstituteUniversity of UtahSalt Lake CityUSA
  2. 2.The Eccles Program in Human Molecular Biology and Genetics and the Nora Eccles Harrison Cardiovascular Research and Training InstituteUniversity of UtahSalt Lake CityUSA
  3. 3.Department of MedicineUniversity of Utah School of MedicineSalt Lake CityUSA
  4. 4.Departments of Medicine and BiochemistryUniversity of Utah School of MedicineSalt Lake CityUSA
  5. 5.Departments of Medicine and Biochemistry, the Nora Eccles Harrison Cardiovascular Research and Training Institute, and the Eccles Institute of Human GeneticsUniversity of Utah School of MedicineSalt Lake CityUSA

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