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Geographic Differences in Antibodies to Glutamic Acid Decarboxylase in Insulin-Dependent Diabetes Mellitus

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Standardization of Epidemiologic Studies of Host Susceptibility

Part of the book series: NATO ASI Series ((NSSA,volume 270))

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Abstract

Major ethnic and geographic differences exist for insulin-dependent diabetes mellitus (IDDM) around the world.1 The disease is most common in people of European descent (Europids) with the highest reported incidence in Scandinavian countries,1,2 particularly in Finland where the incidence exceeds 30 cases/annum per 100,000 population.3 The lowest incidence rates are in Asia, notably Korea at 0.5 cases/annum1 with low rates in Japan3 and China as well.4 These geographic and ethnic differences are possibly due to variations in environmental risk determinants, although genetic differences may also be operative.5

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Zimmet, P., Mackay, I.R., Rowley, M., Knowles, W., Serjeantson, S.W. (1994). Geographic Differences in Antibodies to Glutamic Acid Decarboxylase in Insulin-Dependent Diabetes Mellitus. In: Dorman, J.S. (eds) Standardization of Epidemiologic Studies of Host Susceptibility. NATO ASI Series, vol 270. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1213-8_19

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  • DOI: https://doi.org/10.1007/978-1-4899-1213-8_19

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