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Organofluorine Chemistry pp 555–577Cite as

Properties and Biomedical Applications of Perfluorochemicals and Their Emulsions

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Part of the book series: Topics in Applied Chemistry ((TAPP))

Abstract

During the past 20 years, much attention has focused on the potential applications of emulsified perfluorochemicals (PFCs) in medicine and biology. Of particular interest has been their use as vehicles for respiratory gas transport, primarily as O2-carrying resuscitation fluids designed to supplement conventional blood transfusion. For this reason, PFC emulsions have been frequently, but somewhat inaccurately, referred to as “blood substitutes”. However, important clinical applications for PFCs and their emulsions also exist in areas as diverse as hemodilution and microcirculatory management, cancer therapy, diagnostic tissue imaging, and ophthalmologic surgery. Moreover, PFCs appear to be valuable in both basic and applied research for perfusing isolated organs and for regulating the growth of cell cultures.

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Authors and Affiliations

  1. Mammalian Physiology Unit, Life Science Department, University of Nottingham, University Park, Nottingham, NG7 2RD, England

    Kenneth C. Lowe

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  1. Kenneth C. Lowe
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Editors and Affiliations

  1. The University of Manchester Institute of Science and Technology (UMIST), Manchester, UK

    R. E. Banks

  2. DuPont Central Research & Development, Wilmington, Delaware, USA

    B. E. Smart

  3. Editorial Office of the Journal of Fluorine Chemistry, Birmingham, UK

    J. C. Tatlow

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© 1994 Springer Science+Business Media New York

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Lowe, K.C. (1994). Properties and Biomedical Applications of Perfluorochemicals and Their Emulsions. In: Banks, R.E., Smart, B.E., Tatlow, J.C. (eds) Organofluorine Chemistry. Topics in Applied Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1202-2_27

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  • DOI: https://doi.org/10.1007/978-1-4899-1202-2_27

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  • Print ISBN: 978-1-4899-1204-6

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