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Transformation by Polyomaviruses

Role of Tumor Suppressor Proteins

  • Chapter
DNA Tumor Viruses

Part of the book series: Infectious Agents and Pathogenesis ((IAPA))

Abstract

Since its identification as a tumor virus, SV40 has been a favorite model for understanding the mechanism by which a DNA virus can control the state and growth properties of susceptible cells. From its humble beginnings, the polyomavirus tumor biology field has mushroomed into several new directions, most notably into tumor suppressors. These new branches are now buzzing with activity and touching or merging with other established disciplines including cell-cycle controls, oncogenes, and differentiation.

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Authors and Affiliations

  1. Department of Biology, University of Delaware, Newark, Delaware, 19716, USA

    Daniel T. Simmons

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  1. Daniel T. Simmons
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  1. Institute of Microbiology, School of Medicine, University of Ferrara, I-44100, Ferrara, Italy

    Giuseppe Barbanti-Brodano

  2. University of Pisa, Pisa, Italy

    Mauro Bendinelli

  3. University of South Florida, Tampa, Florida, USA

    Herman Friedman

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© 1995 Springer Science+Business Media New York

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Simmons, D.T. (1995). Transformation by Polyomaviruses. In: Barbanti-Brodano, G., Bendinelli, M., Friedman, H. (eds) DNA Tumor Viruses. Infectious Agents and Pathogenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1100-1_3

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  • DOI: https://doi.org/10.1007/978-1-4899-1100-1_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1102-5

  • Online ISBN: 978-1-4899-1100-1

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