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Peripheral Anionic Site of Wild-Type and Mutant Human Butyrylcholinesterase

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Enzymes of the Cholinesterase Family
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Abstract

Although the existence of a peripheral “anionic” site (PAS) on the surface of AChE has long been demonstrated, there was no direct evidence for a PAS on BuChE. However, structural similarities between the two enzymes and some kinetic complexities of BuChE suggested that the mouth of the BuChE active site gorge may possess PAS components.

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References

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© 1995 Springer Science+Business Media New York

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Masson, P., Froment, M.T., Bartels, C., Lockridge, O. (1995). Peripheral Anionic Site of Wild-Type and Mutant Human Butyrylcholinesterase. In: Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P. (eds) Enzymes of the Cholinesterase Family. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1051-6_48

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  • DOI: https://doi.org/10.1007/978-1-4899-1051-6_48

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1053-0

  • Online ISBN: 978-1-4899-1051-6

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