Fatigue pp 323-338 | Cite as

The Significance of Motor Unit Variability in Sustaining Mechanical Output of Muscle

  • A. J. Sargeant
  • D. A. Jones
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 384)


Neuromuscular function and fatigue have been studied using a wide variety of preparations. These range from sections of single fibers from which the cell membrane has been removed to whole muscles or groups of muscles acting about a joint in the intact animal. Each type of preparation has its merits and limitations. There is no ideal preparation; rather the question to be answered will determine the most appropriate model in each case and sometimes a combination of approaches will be needed. In particular, it is important to understand how the mechanical output of whole muscle can be sustained to meet the demands of a task and to take into account the organized variability of the constituent motor units.


Motor Unit Myosin Heavy Chain Human Muscle Contractile Property Concentric Contraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • A. J. Sargeant
    • 1
  • D. A. Jones
    • 2
  1. 1.Department of Muscle and Exercise Physiology, Faculty of Human Movement SciencesVrije UniversityAmsterdamThe Netherlands
  2. 2.School of Sport and Exercise SciencesThe University of BirminghamEdgbaston, BirminghamUK

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