Catalytic Properties and Classification of Phosphoric Triester Hydrolases: Edta-Insensitive and Edta-Sensitive Paraoxonases in Sera of Non-Diseased and Diseased Population Groups

  • Elsa Reiner
  • Vera Simeon
Chapter
Part of the NATO ASI Series book series (NSSA, volume 266)

Abstract

Phosphoric triester hydrolases (EC 3.1.8) are defined as enzymes acting on organophosphorus compounds, including esters of phosphonic and phosphinic acids, and on phosphorus anhydride bonds; the enzymes are subdivided into paraoxonase (EC 3.1.8.1) and DFP-ase (EC 3.1.8.2) [1].

Keywords

Distribution Profile Organophosphorus Compound Familial Hypercholesterolaemia Phosphinic Acid Paraoxonase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Enzyme Nomenclature, Recommendations (1992) of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. Academic Press Inc., San Diego (1992).Google Scholar
  2. 2.
    E. Reiner, Z. Radie, and V. Simeon. Hydrolysis of paraoxon and pheylacetate by human serum esterases, in: “Enzymes Hydrolysing Organophosphorus Compounds”, E. Reiner, W.N. Aldridge, and F.C.G. Hoskin, eds., Ellis Horwood Ltd., Chichester (1989) 30–40.Google Scholar
  3. 3.
    P. Sprent, “Applied Nonparametric Statistical Methods”, Chapman and Hall, London (1989).Google Scholar
  4. 4.
    E. Pavkovie, V. Simeon, E. Reiner, M. Sueie, and V. Lipovac. Serum paraoxonase and cholinesterase activities in individuals with lipid and glucose metabolism disorders. Chem.-Biol. Interactions, 87 (1993) 179–182.CrossRefGoogle Scholar
  5. 5.
    E. Reiner, I. Gruie, V. Simeon, Z. Pecotie, V. Durrigl, I. Peko-(`ovie, J. Brkljaeie, and D. Hodoba. Paraoxonase activities in sera of non-diseased persons and those with dementia (in Croatian). First Croatian Congress of Clinical Biochemistry. Zagreb (1993), Book of Abstracts 05-P17/13.Google Scholar
  6. 6.
    M. Geldmacher-von Mallincrodt, and T.L. Diepgen. The human serum paraoxonase-polymorphism and specificity. Toxicol. Environ. Chem. 18 (1988) 79–196.CrossRefGoogle Scholar
  7. 7.
    R. Zech, and K. Zurcher. Organophosphate splitting serum enzymes in different mammals. Comp. Biochem. Physiol. 48 B (1974) 427–433.Google Scholar
  8. 8.
    J.R. Playfer, C. Powell, and D.A.P. Evans. Plasma paraoxonase activity in old age. Age and Ageing 6 (1977) 89–95.CrossRefGoogle Scholar
  9. 9.
    MJ. Mackness, D. Harty, D. Bhatnagar, P.H. Winocour, Sh. Arrol, M. Ishola, and P.N. Durrington. Serum paraoxonase activity in familial hypercholesterolaemia and insulin-dependent diabetes mellitus. Atherosclerosis 86 (1991) 193–199.PubMedCrossRefGoogle Scholar
  10. 10.
    B.N. LaDu. Human serum paraoxonase/arylesterase, in: “Pharmacogenetics of Drug Metabolism”, W. Kalow, ed., Pergamon Press, New York (1991) 51–91.Google Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Elsa Reiner
    • 1
  • Vera Simeon
    • 1
  1. 1.Institute for Medical Research and Occupational HealthUniversity of ZagrebZagrebCroatia

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